ID A0A2I9DTY7_9FLAO Unreviewed; 1177 AA.
AC A0A2I9DTY7;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Nitrate reductase {ECO:0000313|EMBL:GBF19044.1};
GN Name=narB {ECO:0000313|EMBL:GBF19044.1};
GN ORFNames=C21_01209 {ECO:0000313|EMBL:GBF19044.1};
OS Arenibacter sp. NBRC 103722.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Arenibacter.
OX NCBI_TaxID=1113929 {ECO:0000313|EMBL:GBF19044.1, ECO:0000313|Proteomes:UP000095208};
RN [1] {ECO:0000313|EMBL:GBF19044.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-21 {ECO:0000313|EMBL:GBF19044.1};
RA Ito K., Nakajima N., Yamamura S., Tomita M., Suzuki H., Amachi S.;
RT "Draft Genome Sequence of Arenibacter sp. Strain C-21, an Iodine-
RT Accumulating Bacterium Isolated from Surface Marine Sediment.";
RL Genome Announc. 4:e01155-16(2016).
RN [2] {ECO:0000313|EMBL:GBF19044.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C-21 {ECO:0000313|EMBL:GBF19044.1};
RA Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBF19044.1}.
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DR EMBL; BDGL02000004; GBF19044.1; -; Genomic_DNA.
DR RefSeq; WP_031443931.1; NZ_BDGL02000004.1.
DR AlphaFoldDB; A0A2I9DTY7; -.
DR Proteomes; UP000095208; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd19942; Fer2_BFD-like; 1.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR InterPro; IPR041575; Rubredoxin_C.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04324; Fer2_BFD; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF18267; Rubredoxin_C; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000095208}.
FT DOMAIN 4..60
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 1177 AA; 131889 MW; 21A0654322A0C244 CRC64;
MQKKNEHKTI CSYCGVGCGI VVEQDSKGNI SVEGDQDYPV NKGMLCSKGK NLNYVAQDVS
DRILYPEMRW SRNHPLQRVS WDTAFDRAAA VFKSIIEKHG PDSVGFYVSG QCLTEEYYLV
NKLTKGFIGT NNIDTNSRLC MSSAVVGYKK MLGEDSVPIS YEDIELSDCF LIAGANPAWC
HPILFRRIEN HKENNPDVKI IVVDPRKTQT CAAADLHLQI LPGTDVILFN AIARWLIEKK
KIDRNFIKKH TVNFDAVKDS AFQLSMKKAA ELCGIPVEDI KKAAMYIGNA NAFISMWTMG
LNQSVIGVSK NVALMNLSLL TGQIGKPGAG PFSLTGQPNA MGGREVGGMA SLLAAHRELG
NPKHRKEVSD FWGGKEIKSE PGYTATEMFD ALENGKMKAV WIICTNPIVS LPNVHKAEKA
LKNANFVVVQ DISHNSETTK FADLLLPAAG WLEKEGTMTN SERRISYLPK VIDAPGEALP
DAEILWKFAQ KMGYHGFDYK NASEVYDEHC LLTKGTEIDI SGLSYDRLKN EGSFQWPVPH
DKHMGTPRLF TDYQFFTNDR KSHFNAPYSL YNKSELTTPE YPLILNTGRI RDQWHTRTKT
GKVKRLLTHI PDPYLEMNKV DAYLRKLKDG DIAVIKSRRG TVRVKVKVNF DIREKVVFLP
MHWGKVLNND FGRANNLTND LVDPVSKEPD FKYCAVEVAK YVKPKQKILI IGAGAAAYRF
IQTYREKNET DELHVFSKEK DPFYNRVLLP EYVSEELSWE ALEKLKKGEL EKLDITLHSG
LGVTQIDRKN KTVMDDDGFE HAYDILVMAT GSRAFVPSEV QINMPGRFTM RERGDADKLR
KYLEDTGLPS EEQHVVIVGG GLLGLELAAA LKNRNVNISI IQRAPRLMER QLDRIASRLL
AEDVSDRGIK VYFDNEVSTV FEERDDKNSL SITLKTGRTI KCNAIVYAIG TRPNIELAKH
SDLKTGRGVV VNEYLQTSDP NIFALGEIAE FRNALFGITS AAEQQADTAA KYILGDFSSI
YNGSILMNIL KFENLDLCSL GMVNAPLDDN SYEEIILMDV SKKYYKKCIV KDDTLKGAIL
MGDKNEFAEF KRLIEEEIEL SEKRNELLRG QKNSVPLKGK LVCSCSQVGE GNLIETINTG
CEDFSKLCSE TGAGLGCGSC KPEIQDILRK QLQTVTS
//
