ID A0A2J5HXE8_9EURO Unreviewed; 607 AA.
AC A0A2J5HXE8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=MFS general substrate transporter {ECO:0000313|EMBL:PLN82063.1};
GN ORFNames=BDW42DRAFT_85403 {ECO:0000313|EMBL:PLN82063.1};
OS Aspergillus taichungensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=482145 {ECO:0000313|EMBL:PLN82063.1, ECO:0000313|Proteomes:UP000235023};
RN [1] {ECO:0000313|Proteomes:UP000235023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 19404 {ECO:0000313|Proteomes:UP000235023};
RG DOE Joint Genome Institute;
RA Mondo S.J., Kjaerbolling I., Vesth T.C., Frisvad J.C., Nybo J.L.,
RA Theobald S., Kuo A., Bowyer P., Matsuda Y., Lyhne E.K., Kogle M.E.,
RA Clum A., Lipzen A., Salamov A., Ngan C.Y., Daum C., Chiniquy J., Barry K.,
RA LaButti K., Haridas S., Simmons B.A., Magnuson J.K., Mortensen U.H.,
RA Larsen T.O., Grigoriev I.V., Baker S.E., Andersen M.R., Nordberg H.P.,
RA Cantor M.N., Hua S.X.;
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. DHA1 family.
CC Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.
CC {ECO:0000256|ARBA:ARBA00038459}.
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DR EMBL; KZ559530; PLN82063.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J5HXE8; -.
DR OrthoDB; 3672446at2759; -.
DR Proteomes; UP000235023; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17323; MFS_Tpo1_MDR_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23502:SF132; BICYCLOMYCIN RESISTANCE PROTEIN; 1.
DR PANTHER; PTHR23502; MAJOR FACILITATOR SUPERFAMILY; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 69..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..503
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 538..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 65846 MW; D51964D001256F8F CRC64;
MSNSTADAGE PVKPTRIPHW RLLFDQGVLT QEIINHDYPG SGTEDDPYSV TWIPNDPRNP
LNTSMTTKWI YTNAMAWATL AVSMVSSAYT GGIEQILQEF RVGTEVGVLG VSLFVVGFAV
GPLAWAPLSE LFGRQYLFLA SYLGLTVFNA AAAGSPNIES LIIFRFLAGA FGSSPLTNAG
GVIADLFPAS HRGLAMSIFA AAPFLGPVLG PVIGGFLGMN AGWQWVLGFL AIFSGALWVF
CGLIVPETYA PVLLQRRAAR LSKLTGKVYR SKLEIDQGKK TLAGAFKTAL SRPWVLLFRE
PIVLLLSIYM AIIYGTLYMM FAAFPIVYRH DRGWNQGISG LAFLGIMVGM MCAVTYTIFD
NKRYVNTQAR HNGFAPPEAR LPPCIVASIA VPIGLFWFAW SNGPEVHWMA SITAGAPFGF
GMVLVFLSLM NYLIDAYTIF AASVLAATSV LRSLFGAAFP LFTTYMYNDL GVHWASSVPA
FLAVACMPFP FLFYKYGASI RARCKYAGES EAFMQKMMAQ VVKPAQEPHA KKIDAVLEEK
STSEQGSTPA DSLADQLGPP GPSPAAHRAQ SIASQASSGP AYATSQTVYD ANPYDIDRVN
TRESFKN
//
