ID A0A2J5I1Q6_9EURO Unreviewed; 1668 AA.
AC A0A2J5I1Q6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN ORFNames=BDW42DRAFT_191979 {ECO:0000313|EMBL:PLN83758.1};
OS Aspergillus taichungensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=482145 {ECO:0000313|EMBL:PLN83758.1, ECO:0000313|Proteomes:UP000235023};
RN [1] {ECO:0000313|Proteomes:UP000235023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 19404 {ECO:0000313|Proteomes:UP000235023};
RG DOE Joint Genome Institute;
RA Mondo S.J., Kjaerbolling I., Vesth T.C., Frisvad J.C., Nybo J.L.,
RA Theobald S., Kuo A., Bowyer P., Matsuda Y., Lyhne E.K., Kogle M.E.,
RA Clum A., Lipzen A., Salamov A., Ngan C.Y., Daum C., Chiniquy J., Barry K.,
RA LaButti K., Haridas S., Simmons B.A., Magnuson J.K., Mortensen U.H.,
RA Larsen T.O., Grigoriev I.V., Baker S.E., Andersen M.R., Nordberg H.P.,
RA Cantor M.N., Hua S.X.;
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|RuleBase:RU004279}.
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DR EMBL; KZ559516; PLN83758.1; -; Genomic_DNA.
DR OrthoDB; 169836at2759; -.
DR Proteomes; UP000235023; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd02735; RNAP_I_Rpa1_C; 1.
DR CDD; cd01435; RNAP_I_RPA1_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 1.10.357.120; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.30.70.2850; -; 1.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR047107; DNA-dir_RNA_pol1_lsu_C.
DR InterPro; IPR015699; DNA-dir_RNA_pol1_lsu_N.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF11; DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 355..682
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT REGION 142..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1336..1451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1400..1422
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1668 AA; 184531 MW; AF4F61C4FA9AA08A CRC64;
MANFARPVAS TISGVDFGVY SEEDVKAVSV KRIHNTPTLD SFNNPVPGGL YDPAMGAWGD
HVCTTCRLSS WACTGHPGHI ELPVHVYNVT HFDQMYRLLR AQCIYCHRLQ ISRVQINKYA
CKLRLLQYGL IDEAAAIDEM GAGAGGKSKG GKKGDASGSE EEEDDDDIIA RRATFVKKSI
REAQASGKLK GLMNGSKNPI AAENRRVIIS EFFKEIVGVK KCAHCKGMSP GYRKDRYSKV
FRKVLSEKSK LAMVTGGFQA PNPLVLLQQA RQFNSKEKEA HSTTHGAEEE VARGNAVLSQ
MESTKQSAGE GGGQYLPSPE VHAAITLLFE KEAEIFSLVY NSRPLSKKES RINADMFFIK
NILVPPNKYR PAAQQGPGEI MEAQQNTPLT QVLKNCDIIN QISKERQSLG SDSASRLRDY
RDLLQAIVQL QDTVNGLIDR DRSGLSGSAL LSAPNGIKQI LEKKEGLFRK NMMGKRVNFA
ARSVISPDPN IETNEIGVPL VFAKKLTYPE PVTNHNFWEM KQAVINGPDK YPGASAIENE
LGQVTNLKFK SLDERTALAN QLLAPSNWRM KGSRNKKVYR HLTTGDVVLM NRQPTLHKPS
IMGHKARVLP NERTIRMHYA NCNTYNADFD GDEMNMHFPQ NELARAEAMM LADADHQYLV
ATSGKPLRGL IQDHISMSTW FTCRDSFFEE EDYHQLLYNC LRPENSHTVS DRIELMPPMV
IRPKRLWTGK QIISTILKNI MPPGRAGLNL KSKSSTPGDR WGEGNEEGTV IFKDGELLCG
ILDKKQIGPS AGGFIDSIHE IYGHTIAGRL ISILGRLLTR FLNMRAFTCG IDDLRLTKEG
DRVRKEKLSE AARIGKEVAL KYVTLDQTTV PDQDGELKRR LEDVLRDDEK QGGLDSVSNA
RTATLSSEIT KGCLPGGLVK PFPWNQMQSM TISGAKGSGV NANLISCNLG QQVLEGRRVP
VMISGKTLPS FRAFETHPMA GGYVCGRFLT GIKPQEYYFH AMAGREGLID TAVKTSRSGY
LQRCLIKGME GLRAEYDSSV REASDGSIVQ FLYGEDGLDI TKQVHLNDFE FLALNHKSIM
SQVNLTSDFH NLEKEEVTNW HKEAMKKVRK TGKPEAMDPA LSIWHPGGNL GSTSEAFSQA
LKKYEDSNPD QVLKDKKKPG TGVISKKGFN TVMNMKYMKS VVDPGEAVGI VAGQSIGEPS
TQMTLNTFHL AGHSAKNVTL GIPRLREIVM TASANIMTPT MTLILNEELS KEHSERFAKA
ISKLSIAEVI DKVQVKERVS TGKVKAKIYD VEITFFPPDE YMAEYAIKAK DLQNALQNKF
IPRLVKLTRN EIKKRDDEKT LKNHSTAQPE IGVSVGTTQE AVRGGEGEDG AIDDDAEEDA
DDAKRARGAQ NRSNQVSYEG PEDEEVDMVR AQDDDEEDDD GNAKPRDIEM NDVSDEGDEE
DQAQESKLRE DDIKGKFAEV HKFKFSPSEG ISCSIQLQYD IATSKLLLLP LVEDAARSAV
IQSIPGLGNC TFVEADDTKG EPACVITEGV NLLAMRDYQD IIKPHSLYTN SIHHMLNLYG
VEAARASIVR EMSDVFEGHS ISVDNRHLNL IGDVMTQSGS FRPFNRNGLV RDGSSPFAKM
SFETTVGFLK DSVIERDFDN LKSPSSRIVV GRVGTVGTGA FDVLAPVA
//
