ID A0A2J6JG44_LACSA Unreviewed; 430 AA.
AC A0A2J6JG44;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LSAT_8X55060 {ECO:0000313|EMBL:PLY61781.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY61781.1};
RN [1] {ECO:0000313|EMBL:PLY61781.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY61781.1}.
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DR EMBL; NBSK01011417; PLY61781.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6JG44; -.
DR STRING; 4236.A0A2J6JG44; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_8X55060_mrna; cds-PLY61781.1; gene-LSAT_8X55060.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_8X55060_mrna; cds-PLY61781.1; gene-LSAT_8X55060.
DR OrthoDB; 5480623at2759; -.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 3.90.810.10; CRIB domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR044785; RopGAP1-5.
DR PANTHER; PTHR23177; MKIAA1688 PROTEIN; 1.
DR PANTHER; PTHR23177:SF35; RHO GTPASE-ACTIVATING PROTEIN GACA; 1.
DR Pfam; PF00786; PBD; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00285; PBD; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50108; CRIB; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
FT DOMAIN 75..88
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT DOMAIN 123..300
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 299..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..347
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 47447 MW; 7B1268E5C61E773A CRC64;
MTGMVMLTRG AGCGGTGGVD GNEATKGGGA TEEEQNQLSL VALLVAALRK SMVACRVDHG
DDQSSGTAAL HQMEIGWPTN VQHLTHVTFD RFHGFLGLPV EFEVEIPCRV PSASVSVFGV
SAESMQCCYD SRGNSVPTIL LLMQERLYAQ GGLKAEGIFR INAENSKEEE VRDQLNRGMV
PEDIEVHCLA GLIKAWFREL PCGVLDGLSP EQVLQCNTED ECCELLKHLK PTETALLNWA
VDLMSDVVEQ EEFNKMNARN IAMVFAPNMT QMSDPLTALM HAVQVMNLLK TLITKTLRER
ERECEESSSS STTTTDGEYS PMSCRSHSRT DEMETSCEMR RQPSSEDGED EDDVESLSEI
EESFLKRLME NENAKDCFKN ELGNLVKGRR TSPTSGFEFQ EESSSSVMSM TDGYVSGVSE
AEVMNKVEEK
//
