ID A0A2J6JLI3_LACSA Unreviewed; 490 AA.
AC A0A2J6JLI3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=CBS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LSAT_4X81321 {ECO:0000313|EMBL:PLY63658.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY63658.1};
RN [1] {ECO:0000313|EMBL:PLY63658.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY63658.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NBSK01010921; PLY63658.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6JLI3; -.
DR STRING; 4236.A0A2J6JLI3; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_4X81321_mrna; cds-PLY63658.1; gene-LSAT_4X81321.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_4X81321_mrna; cds-PLY63658.1; gene-LSAT_4X81321.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17781; CBS_pair_MUG70_1; 1.
DR CDD; cd17782; CBS_pair_MUG70_2; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR13780; AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR13780:SF130; PB1 DOMAIN, CBS DOMAIN PROTEIN-RELATED; 1.
DR Pfam; PF00571; CBS; 4.
DR Pfam; PF00564; PB1; 1.
DR SMART; SM00116; CBS; 4.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 4.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 466..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..99
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 108..166
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 211..268
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 276..332
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 343..435
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 490 AA; 52248 MW; 62F9237BAC697E7D CRC64;
MVLTASSRKK ASENGANDSS RRSITTPRPM GAVGERTVKR LRLSKALTVP ETTTINEACR
RMAARKVDAL LLTDSNALLC GILTDKDIAT RVVARELDLE TTPVSAVMTR NPVFVISDTL
AVEALQKMVQ GKFRHLPVVE NGEVIAILDI AKCLYDAIAR MERAAEKGKA IAAAVEGVEK
HWGTSVSGSN TFIETLRERL FKPTLSTFIS DNSKLVTVSP SDTVLMATKK MLECRISSAV
VTVDSKPIGI LTSKDILMRV IALGLPPEST MVEKVMTPNP ECANIDTPIV DALHIMHHGK
FLHLPVVDRE GIVVAIIDVL HISHAAVASV GSTAGIDNEA ASSMMQKFWD SAMATAPADD
DSDSIRSETH SLTDLITAIL QRVGGEIDRN NLPQILYEDE DKDMVILATD SDLVAAVQHA
RSAGWKGLKL HLDYSGVPRN RKGSLAAGGG GGGGLEHAHP DAWASAYSSV AAGAALVAGL
GVLAFLRRGS
//
