ID A0A2J6JND2_LACSA Unreviewed; 284 AA.
AC A0A2J6JND2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Tetrapyrrole biosynthesis uroporphyrinogen III synthase domain-containing protein {ECO:0000259|Pfam:PF02602};
GN ORFNames=LSAT_5X39421 {ECO:0000313|EMBL:PLY64306.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY64306.1};
RN [1] {ECO:0000313|EMBL:PLY64306.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY64306.1}.
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DR EMBL; NBSK01010635; PLY64306.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6JND2; -.
DR STRING; 4236.A0A2J6JND2; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_5X39421_mrna; cds-PLY64306.1; gene-LSAT_5X39421.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_5X39421_mrna; cds-PLY64306.1; gene-LSAT_5X39421.
DR UniPathway; UPA00251; UER00320.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006782; P:protoporphyrinogen IX biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR Gene3D; 2.60.40.2700; -; 1.
DR Gene3D; 3.40.50.10090; -; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR24057; GLYCOGEN SYNTHASE KINASE-3 ALPHA; 1.
DR PANTHER; PTHR24057:SF70; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF16709; SCAB-Ig; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 209..268
FT /note="Tetrapyrrole biosynthesis uroporphyrinogen III
FT synthase"
FT /evidence="ECO:0000259|Pfam:PF02602"
SQ SEQUENCE 284 AA; 31179 MW; 3B8381C336E9E2A2 CRC64;
MGTQLSTNHF GATKPIYAPE PSDVGRLLEA EVISDGLSIT LTTSGPIEPG LGNYVEALVH
HHDTEFNAKC RETGEIVVIK KVLQDKHYNN RELQVMEMLD HPNVVALKHS FFSTTKKEEL
CLNLVLDFVT ETVSRTATHY TRMNQRMPLT YVKLFTYQAC SYATSFMVNP HTHIYPIFQI
SFSSSFGSNN KAIPSSCGTV SSVERSLYAS IVAVASPSAV GAWVDLLPEI QTWEGSVACI
GETTASAARK LGLTNVSHPS TPGLHGWVDT IFDALRVHNH LSNV
//
