ID   A0A2J6K2F8_LACSA        Unreviewed;       630 AA.
AC   A0A2J6K2F8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=UmuC domain-containing protein {ECO:0000259|PROSITE:PS50173};
GN   ORFNames=LSAT_2X60141 {ECO:0000313|EMBL:PLY69245.1};
OS   Lactuca sativa (Garden lettuce).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC   Lactucinae; Lactuca.
OX   NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY69245.1};
RN   [1] {ECO:0000313|EMBL:PLY69245.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=28401891; DOI=10.1038/ncomms14953;
RA   Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA   Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA   Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT   "Genome assembly with in vitro proximity ligation data and whole-genome
RT   triplication in lettuce.";
RL   Nat. Commun. 8:14953-14953(2017).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PLY69245.1}.
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DR   EMBL; NBSK01008988; PLY69245.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2J6K2F8; -.
DR   STRING; 4236.A0A2J6K2F8; -.
DR   EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_2X60141_mrna; cds-PLY69245.1; gene-LSAT_2X60141.
DR   Gramene; rna-gnl|WGS:NBSK|LSAT_2X60141_mrna; cds-PLY69245.1; gene-LSAT_2X60141.
DR   OrthoDB; 118267at2759; -.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005657; C:replication fork; IBA:GO_Central.
DR   GO; GO:0035861; C:site of double-strand break; IBA:GO_Central.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IBA:GO_Central.
DR   GO; GO:0042276; P:error-prone translesion synthesis; IBA:GO_Central.
DR   GO; GO:0009314; P:response to radiation; IBA:GO_Central.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.1170.60; -; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR   InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001126; UmuC.
DR   PANTHER; PTHR45873; DNA POLYMERASE ETA; 1.
DR   PANTHER; PTHR45873:SF1; DNA POLYMERASE ETA; 1.
DR   Pfam; PF00817; IMS; 1.
DR   Pfam; PF11799; IMS_C; 1.
DR   Pfam; PF21704; POLH-Rev1_HhH; 1.
DR   PIRSF; PIRSF036603; DPol_eta; 2.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR   PROSITE; PS50173; UMUC; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   DOMAIN          14..254
FT                   /note="UmuC"
FT                   /evidence="ECO:0000259|PROSITE:PS50173"
FT   REGION          474..576
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        474..492
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        493..527
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        545..576
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   630 AA;  69877 MW;  EE50A1589D60C3C0 CRC64;
     MPVARPESSD SRVIAHVDMD CFYVQVEQRK QPHLRGQPTA VVQYNSWQGG GLIAVGYEAR
     KDGVKRSMRG DEAKKVCPQI HLITVPVARG KADLNIYRNA GSEVVSILSR KGKCERASID
     EVYLDLTDAA EKLLKETPPE SLESIHEEVL KSHVLGLNSN GDDNHKEIVK EWLQNKNGDP
     RDKLLACGAL IVADLRLQVL QETQFTCSAG IAHNKMLAKL ASGMNKPAQQ TVVPFSSVKD
     LLEALPIKKM KQLGGKLGSS LQVDLGVNTV GDLLKYSEEK LQDLYGVNTG TWLWNTARGM
     NGEEVEERLL PKSHASGKTF RGPSALKTLS SVENWLKELC EELSERLQTD LETNKRIAHT
     LTLHADAYKT TDTDSHKKFP SKSCPLRYGA GKLLEDAINL FQGGLREYMN PMGNQFCGWK
     ITNLSVTASK IIAIPSGTSS ITKYFHCQDP GEKSDLLSTL NDSHESELKM EFGGEQSTIT
     HDESETSFDR VDLSSGHESC STSNQNELQP KLSIKETKIN HLSNGKNIRS NVHKRKPTKE
     KGETSSILRF LQTNSSQLGQ TSSAMEGGSL TKSQNRQTTN TWGYNLDEID QSVVDELPRE
     IQEELYALLP RKKANMVKRG SSIAHYFSPK
//