ID A0A2J6K3J1_LACSA Unreviewed; 669 AA.
AC A0A2J6K3J1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Kinesin motor domain-containing protein {ECO:0000259|PROSITE:PS50067};
GN ORFNames=LSAT_5X49361 {ECO:0000313|EMBL:PLY69642.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY69642.1};
RN [1] {ECO:0000313|EMBL:PLY69642.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-12 subfamily.
CC {ECO:0000256|ARBA:ARBA00034488}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY69642.1}.
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DR EMBL; NBSK01008869; PLY69642.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6K3J1; -.
DR STRING; 4236.A0A2J6K3J1; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_5X49361_mrna; cds-PLY69642.1; gene-LSAT_5X49361.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_5X49361_mrna; cds-PLY69642.1; gene-LSAT_5X49361.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 4.
DR InterPro; IPR044986; KIF15/KIN-12.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR37739; KINESIN-LIKE PROTEIN KIN-12D; 1.
DR PANTHER; PTHR37739:SF8; KINESIN-LIKE PROTEIN KIN-12D; 1.
DR Pfam; PF00225; Kinesin; 3.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 3.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283}.
FT DOMAIN 171..238
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 265..304
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 547..669
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 463..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 334..361
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 465..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 628..635
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 669 AA; 75327 MW; 633472D6862E1957 CRC64;
MFSSVPSDTN LPYPRCRQVS VVGNSVHALR NNYAILGLIS SASNNDFTYK DDEDDGLVVV
VDRDWRSYGS STSSSNGLIE LGSHQDLRLV RRIGEGPWRK GSRVEMWSMV LSGSHRNLVN
LGIKNPVFSL YLAYDIMATM VHEGSYFDEA QFDSKMKELS KKSSNNRRYT KTGVYVENLT
EESVSSIKDV TKLLKKGLSN RRTGATSINI ESSRSHNVFT CVVESRWKEE ESRMDERLTY
NCKCSFLEIY NEQITDLLYP SSTNLQDSLG GNSKTMIIAN VSPSICSATE TLNTLKFAQR
AKLIQNNVSK SHNFDLIQST LFKLFILFSV SKVNEDASGD IMVLQQQIQL LKEELAILKR
NNISRSLAFG PKVIEEATEE HENDCNGHDN KILKVSSKQL KSLETSLTGA LRREKMSEAS
IKQLEVEIEQ LNRLVRQRED NNKSTKMMLK FREDKIHDQI QNEAAQDNKE NNSVRLENTP
TKSVNKPPNP GLSQGGSSRP PISGGVRRNG SFAALSRGLQ NTYTTVNIVE VPHIDLKEDP
SFWMDHNVQV LIRIRPLNNM ELNAQGYNRC LQQESAQCLT WVGHPETRFT FDHVACETID
QETIFRMVGL PMVDNYLSGY NSCIFAYGQT GSGKTHTMLG EINELELKPT PQRGMTPHGA
DSFGDNKIL
//
