ID A0A2J6K8V5_LACSA Unreviewed; 198 AA.
AC A0A2J6K8V5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=HECT domain-containing protein {ECO:0000259|PROSITE:PS50237};
GN ORFNames=LSAT_4X174681 {ECO:0000313|EMBL:PLY71516.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY71516.1};
RN [1] {ECO:0000313|EMBL:PLY71516.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00104}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY71516.1}.
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DR EMBL; NBSK01008295; PLY71516.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6K8V5; -.
DR STRING; 4236.A0A2J6K8V5; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_4X174681_mrna; cds-PLY71516.1; gene-LSAT_4X174681.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_4X174681_mrna; cds-PLY71516.1; gene-LSAT_4X174681.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR045322; HECTD1/TRIP12-like.
DR PANTHER; PTHR45670; E3 UBIQUITIN-PROTEIN LIGASE TRIP12; 1.
DR PANTHER; PTHR45670:SF1; E3 UBIQUITIN-PROTEIN LIGASE TRIP12; 1.
DR Pfam; PF00632; HECT; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|SAM:SignalP};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..198
FT /note="HECT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014400188"
FT DOMAIN 32..101
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT REGION 101..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 198 AA; 21975 MW; FC3C9AE8D8D8F80C CRC64;
MLLPWVYLGI FVSLCAYACG VDFCEYLVAG AVMVNLNNLE EYISLVVDAT VKTGITRQLE
AFRAGFNQVF DVSSLQIFSP SGLDYLLCGR REMWEADTLE ELHESVPTST GNTKETSKAR
ERAANEAHDR SAAESRLRSE RVVVQRAQAD ARERAPIDAK GRAERSVGAC QRYGVIPFSP
NSGLIEWVPN CDTLHQLI
//
