ID A0A2J6KFZ6_LACSA Unreviewed; 563 AA.
AC A0A2J6KFZ6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=ENTH domain-containing protein {ECO:0000259|PROSITE:PS50942};
GN ORFNames=LSAT_8X44300 {ECO:0000313|EMBL:PLY73983.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY73983.1};
RN [1] {ECO:0000313|EMBL:PLY73983.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC {ECO:0000256|ARBA:ARBA00004132}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004600}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY73983.1}.
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DR EMBL; NBSK01007514; PLY73983.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6KFZ6; -.
DR STRING; 4236.A0A2J6KFZ6; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_8X44300_mrna; cds-PLY73983.1; gene-LSAT_8X44300.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_8X44300_mrna; cds-PLY73983.1; gene-LSAT_8X44300.
DR OrthoDB; 3667239at2759; -.
DR GO; GO:0005905; C:clathrin-coated pit; IBA:GO_Central.
DR GO; GO:0030136; C:clathrin-coated vesicle; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005545; F:1-phosphatidylinositol binding; IBA:GO_Central.
DR GO; GO:0032050; F:clathrin heavy chain binding; IBA:GO_Central.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IBA:GO_Central.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IBA:GO_Central.
DR GO; GO:0006900; P:vesicle budding from membrane; IBA:GO_Central.
DR CDD; cd03564; ANTH_N; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.58.150; ANTH domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR014712; ANTH_dom_sf.
DR InterPro; IPR048050; ANTH_N_plant.
DR InterPro; IPR045192; AP180-like.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR22951; CLATHRIN ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR22951:SF89; PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP; 1.
DR Pfam; PF07651; ANTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 4: Predicted;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136}.
FT DOMAIN 24..161
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 336..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..384
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..521
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 563 AA; 63222 MW; BF35E004CAF5B6FD CRC64;
MGTMQTWRKA YGALKDQTKV GLAHVNSDFK DVDVAIVKAT NHVECPPKER HIRKILAYTS
AVRPRADVQY CLHALARRLA KTRNWTVALK TLIVIHRTLR EGDPTFREEL VNFQQRGRVL
QLANFKDDSS PIAWDCSAWV RTYGLFLEER LECFRVLKYD IEAEKIPRLA QGQENKGYSR
TRDLESEELL EQLPALQQLL YRLMGCRPEG AAVGNYLIQY ALALVLKESF KIYCAVNDGI
INLIDKFFEM PRHEAIKALD IYKRAGQQAG SLSDFYDVCK RLELARNFQF PVLREPPQSF
LATMEEYIRE APRLVSGPTQ TLEYPERLML TYKPEAEAEE EDKHEEEETY STSDEIKAVP
INDFLASNHV HEPPPPPPPQ PTFNSRDPDD LLGLNFDDPL PNGSAIEETN ALALAIIPSD
TTSGFQSKDF DPTGWELALV TTPSTNISSI QDRQLAGGLD SLTLNSLYDE GAYRASQQPV
YGSPAPNPFD TPDPFGAPPG QLTPYHLPNP NPNPNPNPFG PYQPNLMMGP APPNPFFDSG
FGQFPVNNGA HPHTNNPFGT TLL
//
