ID A0A2J6KG72_LACSA Unreviewed; 367 AA.
AC A0A2J6KG72;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=VHS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LSAT_9X8340 {ECO:0000313|EMBL:PLY74069.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY74069.1};
RN [1] {ECO:0000313|EMBL:PLY74069.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the TOM1 family.
CC {ECO:0000256|ARBA:ARBA00007708}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY74069.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NBSK01007459; PLY74069.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6KG72; -.
DR STRING; 4236.A0A2J6KG72; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_9X8340_mrna; cds-PLY74069.1; gene-LSAT_9X8340.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_9X8340_mrna; cds-PLY74069.1; gene-LSAT_9X8340.
DR OrthoDB; 609735at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblPlants.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:EnsemblPlants.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:InterPro.
DR CDD; cd03561; VHS; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR044836; TOL_plant.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR46646; TOM1-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR46646:SF5; TOM1-LIKE PROTEIN 2; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 50..178
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 223..310
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
SQ SEQUENCE 367 AA; 40982 MW; DA530B7992B46F61 CRC64;
MDKLDKFKLA SSSFGERLMT GGVQMSRMVG TKMKEILQAP TPESKIVDEA TLETMEEPNW
GLNLRICAMI NSEEFNGTEI VKAIKKKITS GKSAVSQRLS LDLLETCTSN CDKVFSEVAS
EKVLDDMVTM VQDVRTDERN RTKAVRLIRA WGESEDLMYL PVFRQTHLSL KANGIPPASS
PMYQTVESLV HQQPIPPPDR FPLPDIDLMG IEDDTSPYTY TDQSVEQKKE SLLVSRNSLD
LLSSILNSGI DPIPINDELT VSMLEKCKES LPVVQRIAET TTDDDILLFE ALNLHDEIEQ
IISRCAEIKE TMGSEPLEVD DTKQTETIFE TKSNNTEGTG STIDAKVKGN ETSLIHKDES
MEKEEAV
//
