ID A0A2J6KSQ1_LACSA Unreviewed; 1072 AA.
AC A0A2J6KSQ1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PLY78116.1};
GN ORFNames=LSAT_2X27501 {ECO:0000313|EMBL:PLY78116.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY78116.1};
RN [1] {ECO:0000313|EMBL:PLY78116.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY78116.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NBSK01006257; PLY78116.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6KSQ1; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_2X27501_mrna; cds-PLY78116.1; gene-LSAT_2X27501.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_2X27501_mrna; cds-PLY78116.1; gene-LSAT_2X27501.
DR OrthoDB; 1000798at2759; -.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0050832; P:defense response to fungus; IEA:InterPro.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039203; RGA2/3-like.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR36766:SF53; DISEASE RESISTANCE PROTEIN RGA2-LIKE; 1.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT DOMAIN 13..96
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 169..412
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1072 AA; 122824 MW; 8CD75ECF5320F838 CRC64;
MAEALVTIAA EGILKKVLSI AAGELAIAWG YEEKLTSLHR TLELIRAKLH DAKRQKGTEA
VMVWLKQLKD VVGEADDVLD EVHYEMLRRQ IKKRDQVARK ASCLPSLKKF SFHNEIGHKI
EKINEMLDTI YTQANGLGLQ NERPVDPVPD HLYRETIPHS EEFKIVGRDD DVLRIIQLLT
QSRTEEKLTI VPIVGMGGIG KTALAKSVYN DERIEHHFNV KAWLCVSVKI DIITLLRKIY
ESLAGKKPQS DSKVNLIKSL EEELGSKRYF LVLDDVWVEE RTYWEEFRRC MLGVNSQNGS
GILVTTRKLE IGTTGMKADL CHLKGLSDDH CWDIFRERAF VAGTSQSPEL EEIGRQIVKK
CDGLPLLLNV IGGMLANYHD KEKWLSIKDS NVWDLEEERD RVQKSLELSF DNLPNSIVKQ
CFAYCSIFKK DKVMKREELV QLWMALGLVQ ADEEKNKEME DVGNDIFEML VSNSLFQDVE
RDELYGHITH CSMHDLVHDL SVSLSKHESL RLVDVTDADI ACIPQVKHLS FYHELNDDDE
FKAKVSMFIE RNTVARSLKT LFIKGKVEKK FSFQPLKCMR ILKLNGCGTE KIDDSIGELV
HLRYLNLSNT KIRVLPKSIG KLYHLQTLKL QGCDDLKFPE AMRNLISLRY FMCDEDIPTY
VLGQLISLRK LSSVKVVGRK GHGIEVLRHL NNLTRSLCIS NLENVRSKED AVKADLSSKK
NLNKIEFIWS EYDRGANRND KEVLGGLQPP GGVKILTINN FCGDNFPEWV MKMAVNIDGK
WMPLDKLVKI RLSGCSSCLS LPTLEHLPHL QHLWLQNMDS LTCLRSSDVT GSTKPLSPSL
RSLHLYSMER LEKWIDREPN SSKMISPVLE ALSIWTCPKI ILLDECHPHP LVFLRIWDCT
GLVSIKSLQG LTSLENLLID DCPSLSEITN LPNQCYSLNT LHITKCGKLT SLPQKMFDCF
AFLNKLELGP FSKELDFFPS LQGIQKLRNH LHYLELRGWD HWESIPEEIQ HLTSVYWLEI
DGFGIQELPM WLTNMSSIRY LSFYDCNRLN KETVRRGAPR ESNFVRLNNE VC
//
