ID A0A2J6KVQ9_LACSA Unreviewed; 543 AA.
AC A0A2J6KVQ9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=LSAT_2X17301 {ECO:0000313|EMBL:PLY96984.1}, LSAT_5X27220
GN {ECO:0000313|EMBL:PLY79172.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY79172.1};
RN [1] {ECO:0000313|EMBL:PLY79172.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY79172.1}.
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DR EMBL; NBSK01005981; PLY79172.1; -; Genomic_DNA.
DR EMBL; NBSK01000604; PLY96984.1; -; Genomic_DNA.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_2X17301_mrna; cds-PLY96984.1; gene-LSAT_2X17301.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_5X27220_mrna; cds-PLY79172.1; gene-LSAT_5X27220.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_2X17301_mrna; cds-PLY96984.1; gene-LSAT_2X17301.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_5X27220_mrna; cds-PLY79172.1; gene-LSAT_5X27220.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF602; DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS)-RELATED; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
FT DOMAIN 13..177
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 543 AA; 62089 MW; 3F89B44CF914DF65 CRC64;
MASSSTLFIQ HSYKYDVFLS FSGEDTRKSF VDHLYVALQR QGIHTYKDDE SLEKGKKINV
ELLKSIQDSK FYIIIFSKNY ASSSWCLDEL VKIMECQKNP EHIAYPVFYD VEPSEIRKQL
GGVGKAFAKH KKKGELKKWK EVLEEASNLA GWDLRNTDDG HEAKLINKIV EKISVELRFS
NLNVDEKLVG MESRINDIVS SLETGAEDVR IIGIKGIAGG GKTTLARAIF DKIHFQFEGK
SFVENVREVA KASLSGLQSL QEQVLSNVLN DKRITVGSVH DAKSMMKKML SGKKVLLILD
DVDDLDQMDA LAGGVNWLKS GSRIIITTRD EQVLVAYRVM WIHDVSLLSH KEAICLFSRY
AFGRDIPIQR YNDLSLKVVH YAAGLPLTIR VLGSFLCGKD ELEWKDALNR LKTIPLKETQ
EKLEISYTGL EDDYKEIFLD VACLLKGWLK DDAIRALESC GFHARNGLRV LEQKSLMTIS
PYQRLGMHDH IAEMGRNIVR RLHPDEPLRH SRLWIRREIE DVLANDLVRM MFTYMWKNLT
SFH
//
