ID   A0A2J6KWL0_LACSA        Unreviewed;       636 AA.
AC   A0A2J6KWL0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN   ORFNames=LSAT_3X60700 {ECO:0000313|EMBL:PLY79425.1};
OS   Lactuca sativa (Garden lettuce).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC   Lactucinae; Lactuca.
OX   NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY79425.1};
RN   [1] {ECO:0000313|EMBL:PLY79425.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=28401891; DOI=10.1038/ncomms14953;
RA   Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA   Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA   Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT   "Genome assembly with in vitro proximity ligation data and whole-genome
RT   triplication in lettuce.";
RL   Nat. Commun. 8:14953-14953(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PLY79425.1}.
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DR   EMBL; NBSK01005894; PLY79425.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2J6KWL0; -.
DR   STRING; 4236.A0A2J6KWL0; -.
DR   EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_3X60700_mrna; cds-PLY79425.1; gene-LSAT_3X60700.
DR   Gramene; rna-gnl|WGS:NBSK|LSAT_3X60700_mrna; cds-PLY79425.1; gene-LSAT_3X60700.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProt.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR008266; Tyr_kinase_AS.
DR   PANTHER; PTHR48053:SF128; CONCANAVALIN A-LIKE LECTIN_GLUCANASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR48053; LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED; 1.
DR   Pfam; PF00560; LRR_1; 10.
DR   Pfam; PF13855; LRR_8; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   PRINTS; PR00019; LEURICHRPT.
DR   SMART; SM00365; LRR_SD22; 4.
DR   SMART; SM00369; LRR_TYP; 6.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          461..636
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   BINDING         490
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   636 AA;  70753 MW;  5AC206A273DB163F CRC64;
     MYLNENKFSG QIPTNIGDLK SLTDLVMTNN HFCGSIPSSL ANLSNLQYMY LNENKFSGQI
     PTNIGDLKSL TYLHMSQNQL GGFIPSSLAN LSNLQYMYLN ENKFSGHIPN DLGNLKSLYG
     IEAIQNQLSG FIPSSLANLS NLQYLYLADN ILSGSIPQGL GSLELCHLQM FDNQLSGHLP
     EDLCHGGKLQ IFTIDGNQLT GPISRGLRNC SSLIRTRFDQ NQFIGDVSSS FGIYPRLEYL
     DISHNNFHGQ LSQKWSKCNH LTALLMAYNN ISGSIPPEFA NSTQLQRLDL SSNHLVGEIP
     KEFGKMKSML NLSLANNRLS GIIPTELEYC ELLEALDLST NRLNGSIPRS ISQWKHIHYL
     NLSNNKLSEK IPSEIGKLVQ LTEFDLSQNL LTQEIPSEVE SLKNLQKLNL SHNRLSGSIP
     NTFTSLPSGI DIDLSDNELT GPVPLCSNFL NASLQGNPDN FDEAYAIGTG GYGTVYKAQL
     QPNNVVAVKK LHSSSENVDQ NGFLNEVRTL TNIRHRNIVK LYGYCSHARH SFFIYEYLEK
     GSLGSILRID DLAKELDWLK RVSIVKAVAN GLAYMHHDCS PPIIHRDISI ANILLDYDYE
     AHISDFGTSK LLKLHSSNWT TIEGTHGYIA PSNVIL
//