ID A0A2J6L8V5_LACSA Unreviewed; 371 AA.
AC A0A2J6L8V5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=HSF-type DNA-binding domain-containing protein {ECO:0000259|PROSITE:PS00434};
GN ORFNames=LSAT_4X26761 {ECO:0000313|EMBL:PLY83634.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY83634.1};
RN [1] {ECO:0000313|EMBL:PLY83634.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|RuleBase:RU004020}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY83634.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NBSK01004716; PLY83634.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6L8V5; -.
DR STRING; 4236.A0A2J6L8V5; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_4X26761_mrna; cds-PLY83634.1; gene-LSAT_4X26761.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_4X26761_mrna; cds-PLY83634.1; gene-LSAT_4X26761.
DR OrthoDB; 1117127at2759; -.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0034605; P:cellular response to heat; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR10015:SF434; HEAT STRESS TRANSCRIPTION FACTOR A-4B-RELATED; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR PRINTS; PR00056; HSFDOMAIN.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00434; HSF_DOMAIN; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 53..77
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS00434"
FT REGION 103..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 371 AA; 41964 MW; E3696ACA2FE22CB5 CRC64;
MDGSQGGSNS SPPFLTKTYE MVDDPLTDHI VSWSHTGSSF VVWNPPEFAS ELLPKYFKHN
NFSSFVRQLN TYGFRKIDPD QWEFANDEFL RGQRHLLKKI HRRKPIHSHS TPPQGSTPAT
LSPSERQEYE DDIQKLKHET NSLRLVLQRH KQENQEYEQN FATLRERVQK IQLRHKKTMS
FLAQILEKPG FLESNTRKRR LLITTYLHGE ANADDNGNPD SIPLLNKLES SLKFWTDFVN
DIVKVSGEET YDFGILAQPE KQVSGDFNEV SRVKSSGIDV NAAPAAATDG DGGAATVPAV
QAGANDVFWE QFLTETPGGG DTQEVQSARR DVINKHDELG QRKSLWNTNN NLDKITEKMG
NLSPSGKLDV R
//
