ID A0A2J6LI39_LACSA Unreviewed; 410 AA.
AC A0A2J6LI39;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Equilibrative nucleoside transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=LSAT_5X131941 {ECO:0000313|EMBL:PLY87012.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY87012.1};
RN [1] {ECO:0000313|EMBL:PLY87012.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY87012.1}.
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DR EMBL; NBSK01003673; PLY87012.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6LI39; -.
DR STRING; 4236.A0A2J6LI39; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_5X131941_mrna; cds-PLY87012.1; gene-LSAT_5X131941.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_5X131941_mrna; cds-PLY87012.1; gene-LSAT_5X131941.
DR OrthoDB; 239997at2759; -.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IBA:GO_Central.
DR InterPro; IPR002259; Eqnu_transpt.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF75; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER, MAJOR FACILITATOR SUPERFAMILY DOMAIN PROTEIN-RELATED; 1.
DR Pfam; PF01733; Nucleoside_tran; 2.
DR PIRSF; PIRSF016379; ENT; 1.
DR PRINTS; PR01130; DERENTRNSPRT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 26..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 410 AA; 45203 MW; 863C9C65FCBEF8C9 CRC64;
MESLNLKVDM NPNKIHDVEP KDTYQIAYMI HFFLGAGYLV PWNAFITAVD YFQYLYPTKH
INKVFSVGYM SAAVTVLLTL LCWPKSCRIQ LPSVRTRMNV GQALFISALM VAPVTDWIDH
GNQSEIGSNV AFVVLVSMVM VSGLADGLVG GSLVGATGEL PGRYMQAVFA GNATAGLMVS
ILRVITKASL PHTQKGLRTS TQIYFVFSAL IVLICVICTN VLDKLPVIRY YRNKSRNEAT
GHMAIGTHFC VVVKKIRWFV TAGLVIYIVS LSIFPGYLSE NVSSDYFKDW YPIILITTFN
VGDFLGKCLT AIYLPRRSKG AIWCCMARVV FYPLFMGCIH GPKWMGSEVP VIVLTLMLGV
SNGYLTSVLM ILAPKSVPVE ESEVVGIAME TSLVVGLVVG SAFGWLWNLL
//
