ID A0A2J6LU96_LACSA Unreviewed; 941 AA.
AC A0A2J6LU96;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Formin-like protein {ECO:0000256|RuleBase:RU361260};
GN ORFNames=LSAT_5X4561 {ECO:0000313|EMBL:PLY90784.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY90784.1};
RN [1] {ECO:0000313|EMBL:PLY90784.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000256|ARBA:ARBA00025793}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY90784.1}.
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DR EMBL; NBSK01002330; PLY90784.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6LU96; -.
DR STRING; 4236.A0A2J6LU96; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_5X4561_mrna; cds-PLY90784.1; gene-LSAT_5X4561.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_5X4561_mrna; cds-PLY90784.1; gene-LSAT_5X4561.
DR OrthoDB; 623207at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213:SF359; FORMIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR23213; FORMIN-RELATED; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..941
FT /note="Formin-like protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014372534"
FT TRANSMEM 159..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 463..903
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 203..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 892..941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..336
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..449
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 897..918
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 941 AA; 102724 MW; C08D29BE0AD2BE21 CRC64;
MGAKVVILFM TIIILLYPLA EAIESDRHRQ QLPPDNQMYL EETMDEDTAE LLWVNCGAEL
MYTMEAFEDL EYCGCDKSIT GKERIIKAIN VQDPHVKKTI LDCLKEKRIV LSKLRKDKLS
TRTSLYIEYL VSFLSNPNII IDHVHGRRKL GETVSQGTVV VAVIVTAIFT MCLAGLLFYC
YIRKHGGIQN NDEKPLLSLS MGGFRRKSTD NQSNGQKNDS PMDARVSVDP DASGITNVND
GSSLDPSMQQ PRVKESLRHT LKPRAVRAES SLRPTGKTEF ALRPSAGNTG SPVGVGGIES
SPQLESSEQQ PPPTGSSLAP PALTADPPPP PAHVVPLVQL TEPKPSSDEP PPPQTQGAAP
LPRTQGASPL PSQTQGAPPS PSQTQGAPPP PPPTGEAGGA PPPPPPVAEG SGAPPPPPPT
GGSGSGAPPP PPKLGGNAGA PPPPPLRGSV ARPLSAALRL RRTEQVDASK AKLKPFFWDK
VMAKPDQQMV WDKIRSGSFQ FNEEMIESLF GYQAAEKNKD QDTKNAATKN KDPPVHFVQI
IDPKKAQNLS ILLKALNVTT EEVSAALIEG NELPLEIVQT LLKMAPTSEE ELKLRLYDGD
LHRLGPAERF LKVLVEIPYA FRRLESLLFM CTLQDEESNI KESLETLEAA CVQLKKSRLF
LKLLEAVLKT GNRMNVGTFR GSATAFKLDT LLKLSDVKGV DGKTTLLHFV VQEIMRSEGI
RAVRSAKEGK SISSIKTEDL LLEPPPEEAD EHYCKLGLEV VSCLSSELED VKRAAIIDAD
GLTSSVSKLG NALLKARESL NTDMKILEEQ LEEEADEFWL ILSTFVENAD KQITWMLEEE
KRIMALVKST ADYFHGKSGK DEGLRLFTVV RDFLIILEKV VKEIQAAPIK PLKKKADMSS
GTQKKEDMSS DPERKDDQNQ ATNGAPTLTR IPNCQIPSPP D
//
