ID A0A2J6M166_LACSA Unreviewed; 1115 AA.
AC A0A2J6M166;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LSAT_6X98720 {ECO:0000313|EMBL:PLY93259.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY93259.1};
RN [1] {ECO:0000313|EMBL:PLY93259.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY93259.1}.
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DR EMBL; NBSK01001688; PLY93259.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6M166; -.
DR STRING; 4236.A0A2J6M166; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_6X98720_mrna; cds-PLY93259.1; gene-LSAT_6X98720.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_6X98720_mrna; cds-PLY93259.1; gene-LSAT_6X98720.
DR OrthoDB; 551430at2759; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR CDD; cd13365; PH_PLC_plant-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 3.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR013591; Brevis_radix_dom.
DR InterPro; IPR027988; BRX_N.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22870:SF386; FYVE-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR Pfam; PF08381; BRX; 1.
DR Pfam; PF13713; BRX_N; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF16457; PH_12; 1.
DR Pfam; PF00415; RCC1; 6.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS51514; BRX; 1.
DR PROSITE; PS00626; RCC1_2; 3.
DR PROSITE; PS50012; RCC1_3; 6.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT REPEAT 298..349
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 350..404
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 405..456
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 468..519
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 520..571
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 572..623
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 628..690
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 1031..1086
FT /note="BRX"
FT /evidence="ECO:0000259|PROSITE:PS51514"
FT REGION 135..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 747..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 781..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..1023
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1089..1115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 816..892
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 142..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..974
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 993..1023
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1090..1115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1115 AA; 121296 MW; D087E32BC486FB6C CRC64;
MADLVSYGNA DRDTEQTLIA LKKGAQLLKY GRKGKPKFCP FRLSHDESSL IWISTSGERN
LKLSLVSRIV PGQRTAVFRR YLRPEKDYLS FSLIYNNGKR SLDLICKDKV EAEVWIAGLK
ALISGQGGRS KIDGWSEGGL NIEENKDSTS NSASDNSISA PPDLSSPDAS FGSNSNTSPM
NYQNSSTFEK STTMFDQTNI QVKGFGSDAF RVSVSSAPST SSHGSAQDDY DALGDVYIWG
EVICDNNNII KLGPDKNPNS STTRADVLLP RPLESNLVLD VNHISCGVRH AALVTRQGEV
FTWGEESGGR LGHGFQKDVT QPRLLESLSV SNIDFVACGE FHTCAVTMSG ELYTWGDGTH
NAGLLGHGTN VSHWIPKRIG HPLEGLKIAS VTCGPWHTAL ITSTGQLFTF GDGTFGVLGH
GDREHVPCPR EVESLLGLRT IAVACGVWHT AAVVEVIVTR SSTGVSSGKL FTWGDGDKNR
LGHGDREPRL KPTCVPSLID YNFHKVACGH SLTVGLTTSR HVFTMGSTVY GQLGNPQCDG
KLPCLVEDKL SGEPVDEIAC GAYHVAVLTS RNEVYTWGKG ANGRLGHGDI EDRKTPTLVE
SLKDRHVKFI SCGSNYTASI CLHKWVSGTE QSQCSSCRQA FGFTRKRHNC YNCGLVHCHS
CSSRKALRAA LAPNPSKPHR VCDSCFVKLS KMAEAGVGSR RNVMPRLSGD NKDRLDKSDM
RLAKSGLPSN HDLIKLLDNK AARQGRKADA FPVGRSSQAG GGGGGGDFRY AVPRPIVTQS
GVNSRAVSPF SRKSSPPRSA TPVPTTSGLS FSKNVADSLK RTNDLLNQEV LKLRGQVDSL
RHQCEIQEAE LQKSRKQSQE AMVLAAEESA KCNAAKDVIK SLTSQLKDMA ERLPPGSYDL
DSIKLPNGLD SNSMLHNPDT SEENQIITPM DTISSINETS GPTESFAGFT ESVRTSNGND
GDSDARSLNG TTGAVVEMGN KYLPDHAPPS QEAENNGFKS RNPASNSNNN NHHNNNNNNN
NTYNATDQVE AEWIEQYEPG VYITLVALRD GTRDLKRVRF SRRRFGEHQA ETWWSENREK
VYERYNVRGG SDKSSVSAAQ TARRSGESLG TPSQY
//
