ID A0A2J6M201_LACSA Unreviewed; 830 AA.
AC A0A2J6M201;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Beta-adaptin-like protein {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=LSAT_5X45441 {ECO:0000313|EMBL:PLY93539.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY93539.1};
RN [1] {ECO:0000313|EMBL:PLY93539.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- FUNCTION: Subunit of clathrin-associated adaptor protein complex that
CC plays a role in protein sorting in the late-Golgi/trans-Golgi network
CC (TGN) and/or endosomes. The AP complexes mediate both the recruitment
CC of clathrin to membranes and the recognition of sorting signals within
CC the cytosolic tails of transmembrane cargo molecules.
CC {ECO:0000256|PIRNR:PIRNR002291}.
CC -!- SUBUNIT: Adaptor protein complexes are heterotetramers composed of two
CC large adaptins (beta-type subunit and alpha-type or delta-type or
CC epsilon-type or gamma-type subunit), a medium adaptin (mu-type subunit)
CC and a small adaptin (sigma-type subunit).
CC {ECO:0000256|PIRNR:PIRNR002291}.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY93539.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NBSK01001661; PLY93539.1; -; Genomic_DNA.
DR STRING; 4236.A0A2J6M201; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_5X45441_mrna; cds-PLY93539.1; gene-LSAT_5X45441.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_5X45441_mrna; cds-PLY93539.1; gene-LSAT_5X45441.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015151; B-adaptin_app_sub_C.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF4; AP-4 COMPLEX SUBUNIT BETA-1; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF09066; B2-adapt-app_C; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 1.
DR SMART; SM01020; B2-adapt-app_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR002291};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 705..823
FT /note="Beta-adaptin appendage C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01020"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 830 AA; 91798 MW; 2617949EB9391336 CRC64;
MAPPAQSQRS PSPSQPSGKG EVSDLKMQLR QLAGSRAPGT DDSKRDLFKK VISYMTVGID
VSSVFSEMVM CSATSDIVLK KMCYLYVGNY AKYNPDLALL TINFLQRDCK DEDPMIRGLA
LRSLCSLRVP NLVEYLVGPL GAGLKDGNSY VRMVAAVGVL KLYHISASTC LDADFPALLK
HLMLNDPDAQ VVANCLSALQ EIWGLEASTS EEAVREREAL ISKPIIYFLL NRIKEFSEWA
QCTILELVSK YAPPDSNEIF DIMNLLEDRL QHANGAVVLA TIKLFLQLTL SMTDVHQQVY
ERIKAPLLTL VSSGSQEQSY AVLSHLHLLV MRAPMLFASD YKHFYCQYNE PFYVKKLKLE
MLTAVANESN TYEIVTELCE YAANVDIPIA RESIRAVGKI ALQQYDVNAI VDRLLQFLEM
EKDYVTAETL VLVKDLLRKY PQWSHDCIAV IGNISSNNVQ EPKAKAALIW MLGEYAQDMQ
DAPYALEGLI EDWEDETSPE VRLHLLTAVM KCFFRRPPET QKALGAALAA GLADMHQDVH
DRALFYYRLL QHSVSVANSV VNPVKQAVSV FADTQSSEIK DRIFDEFNSL SVLYQKPSYM
FTDKEHQGPY AFSEELGHLS IGAEPAAAAA AADVDXLDIS AAAAADEEHI QANDGDLLLT
TTEKEESRAH DSDYSLSQLS VQQPTSTIDD IFGLGLSVAP APPPLKLNAK PVLDPATFQQ
KWRQLPVAVS QEGSISPQGV AALTSSLEPL LRHMQAHHIN CIASGGKSPN FKFFFFAQKA
SDSSNFLVEC IINSSTCKAQ IKIKADDQTT SQPFFSLFQS ALSNFGIIAS
//
