ID A0A2J6M2H2_LACSA Unreviewed; 1816 AA.
AC A0A2J6M2H2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PLY93704.1};
GN ORFNames=LSAT_2X124500 {ECO:0000313|EMBL:PLY93704.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY93704.1};
RN [1] {ECO:0000313|EMBL:PLY93704.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SIMILARITY: Belongs to the APC1 family.
CC {ECO:0000256|ARBA:ARBA00010547}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY93704.1}.
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DR EMBL; NBSK01001635; PLY93704.1; -; Genomic_DNA.
DR STRING; 4236.A0A2J6M2H2; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_2X124500_mrna; cds-PLY93704.1; gene-LSAT_2X124500.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_2X124500_mrna; cds-PLY93704.1; gene-LSAT_2X124500.
DR OrthoDB; 180933at2759; -.
DR GO; GO:0005680; C:anaphase-promoting complex; IBA:GO_Central.
DR GO; GO:0060090; F:molecular adaptor activity; IBA:GO_Central.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; IBA:GO_Central.
DR GO; GO:0070979; P:protein K11-linked ubiquitination; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR024990; Apc1.
DR InterPro; IPR048971; Apc1_3rd.
DR InterPro; IPR041221; APC1_C.
DR InterPro; IPR046794; Apc1_MidN.
DR InterPro; IPR049255; Apc1_N.
DR InterPro; IPR011989; ARM-like.
DR PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR Pfam; PF12859; ANAPC1; 2.
DR Pfam; PF21282; APC1_3rd; 1.
DR Pfam; PF18122; APC1_C; 1.
DR Pfam; PF20518; Apc1_MidN; 1.
PE 3: Inferred from homology;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 34..273
FT /note="Anaphase-promoting complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12859"
FT DOMAIN 304..516
FT /note="Anaphase-promoting complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12859"
FT DOMAIN 522..785
FT /note="Anaphase-promoting complex subunit 1 middle"
FT /evidence="ECO:0000259|Pfam:PF20518"
FT DOMAIN 1459..1521
FT /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF21282"
FT DOMAIN 1596..1761
FT /note="Anaphase-promoting complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18122"
SQ SEQUENCE 1816 AA; 201379 MW; 16A4E921504F1DF7 CRC64;
MSSIGVRHLT ILGEFKPFGL IAEALDGKPA DEVTDEYEYF LFDPEVTRQQ DEAESADNEA
SSSLSDRSDH ELFIRGNRII WTVGARVYKR FTLPGPVIMA CWCRMGDLSE ACLCVLQVDS
LTVYSTSGDA VSIPLPRAVA SIWPLPSGLL LQQTNESNSS THSLFSSSSP LLTALDIPRS
KKDMGYSPQQ TFNLRSSWDH MIKVDRASVS SHLILKDPLE EPQPIHIEER GKLNTMKEYD
EKTIWTSDLI PLMASYHKGK MQHSLWTAEV MNSNLEAVDS VLPDVMLSKK FFFRRIWQGK
GAQTAASEVF LATDNDATPI ICFLLQEQKK LLAVRLQCVE LNSEILYDIR PDMSWSIPAI
AAAPVVVTRP RVKVGQLPYR DIIVLAPENT LVLYSGKQCL CRYVLPSFQD HGGVSHNVKP
LEAPTAFQDV KVVGLADAVE GRINVIVNNG QMLRCTFRRY PSSSLANDCI TAMAEGLEAN
LYNHFVGLLW GNGDSAYLSK VDSPVDTEWE SFCAIILYIF GKDRKNPQIH SGSSWDFLVN
SSFHEKYSKS HFMSGFSRRI SLQSDQSRTA SQHLDTSHTV ESLLEILDLL HAVYESLKLN
HLRKRDLGLL VALLCEVSKF LGESGYLDYY IRDFPTLSRK YSFHQTSLSQ RTPPSLFRWL
ENCLRHGCTS TSSADLPDLM RKDGSSVVSW ARKIVSFYSV LCGGKIEGNK LSSDVYCKFA
TGSASSPEEL TVLAMVGERF GLQQLDLLPA GVSLPLRHVL DKCRECPPTD WPASAYVLLG
REDLSLSCLA HSNKFTEINS SNTVTSVSMS TPYMLHLRPV TIPSSVSDAT GLDNSKLEDT
DSVDGSTIDG MEHIFNSSTQ LRYGRDLRLN EVRRLLCSAK PVAIQTPVNP TASDQDLQQA
QLWQLAQRTT ALPVGRGAFT LSTTCTLLTE ALPVPKLMLA GRLPAQQNAT VNLDPNIRNI
QELKSWPEFH NAVAAGLRMA PLQGKMSRTW IVYNKPEEPN VTHAGLLLAL GLHGHLDVLN
ITDIYQYYSQ EHESTTAGLM LGLAASYRGT MQPAISKSLY VHIPARHSSS FPELELPTLL
QSAALVSVGL LYEGSAHPQT MQILLGEIGR RSGGDNVLER EGYAVSAGFS LGLVALGRGL
DATGFMDTLV GKLFQYAGSK EFHLERSHLS NGSMDDHNRG SGQMMDGTQI NIDVTAPGAI
IALGLMYLKT ESQVILSRLC IPQTHFELQY VRPDFIMLRV ISRNLIMWSR IYPSEDWIQG
QIPKVVLNGI KGLTDEMEMD SEAVVKAYVN IVAGACISLG LRFAGTKDGN AQDLLYSYAV
AFLNEIKALP VKILPGFPRG LSQYVDRGTL ETCLHLIALS LSVVMAGSGH LQTFRLLRFL
RCRNSADGHV NYGTQMAVSL AIGFLFLGGG MRTFSTSNSS IAALLITLYP RLPTGPNDNR
CHLQAFRHLY VIATEARWVQ TVDVDSGLPV YAPLEVTVKE TDHYAETSFC EVTPCILPER
ALLKTVRVCG PRYWPQVIEL NPEEKPWWNG GEKKDPFNSG ILYIKRKVGA CSYVDDPIGR
QSLLSRAMHK VFGLGSLRGC SSSNNDDDEA AVSVNQLVST FSSDPSLIAF GALCSDHSWN
IKLDTDFQEF CLQVLFECVS KDRPALLQVY LSLYTTVASM ADEVTSGIPP LLNDSQFLPS
LKLALAYNDA LVKGRFMSSR GSIVQSTFLG SLNKRVQELL AYSPCLRNNI ILNDYFRTGK
WSEDDNISTL VSWYLQWYNV PPPSLIQAGI KKLKSIQSQT QTQRQRPSTI PLLRLLFPGT
HINAINEIHK FMLSDR
//
