ID A0A2J6M2Q3_LACSA Unreviewed; 347 AA.
AC A0A2J6M2Q3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=HSF-type DNA-binding domain-containing protein {ECO:0000259|PROSITE:PS00434};
GN ORFNames=LSAT_5X185701 {ECO:0000313|EMBL:PLY93866.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY93866.1};
RN [1] {ECO:0000313|EMBL:PLY93866.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|RuleBase:RU004020}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY93866.1}.
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DR EMBL; NBSK01001622; PLY93866.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6M2Q3; -.
DR STRING; 4236.A0A2J6M2Q3; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_5X185701_mrna; cds-PLY93866.1; gene-LSAT_5X185701.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_5X185701_mrna; cds-PLY93866.1; gene-LSAT_5X185701.
DR OrthoDB; 1113987at2759; -.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0034605; P:cellular response to heat; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR10015:SF376; HEAT SHOCK TRANSCRIPTION FACTOR A7A-RELATED; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR PRINTS; PR00056; HSFDOMAIN.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00434; HSF_DOMAIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 89..113
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS00434"
FT REGION 10..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 165..206
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 139..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..311
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 39518 MW; 00664A84F7FFBB54 CRC64;
MNPFFSVVKE EYPSSGGGGG GSDGVRRPTA IQAPLPQPME GLHDAGPPPF LTKIYDMVDD
RSIDHIVSWS RGGQSFTVLD PHAFATNLLP RYFKHNNFSS FVRQLNTYGF RKIDPDVWEF
ANEAFVRGQR HVLKNIKRRR APSSSSSSSS AASQGCPESF GLDEVGRLKH EKQVLMMELV
NLRQQQQNTR AQLQAMEVRI RGTEKKQQKV MSFLAKAMQN PEFVRKLVQH GRRQDLRDAI
RGFDGVESGE SSRTRNKLIK DEPEEEEFSQ VSELEALALE IQGFGRAKRN QEEEEEEVVE
EEEEANEMCE EKELDDEFWE ELFSERSGVE DVNFLADKLD FLGSNPK
//
