ID A0A2J6M4A1_LACSA Unreviewed; 223 AA.
AC A0A2J6M4A1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=3-hydroxyacyl-CoA dehydrogenase NAD binding domain-containing protein {ECO:0000259|Pfam:PF02737};
GN ORFNames=LSAT_7X97701 {ECO:0000313|EMBL:PLY94337.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:PLY94337.1};
RN [1] {ECO:0000313|EMBL:PLY94337.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|RuleBase:RU003707}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLY94337.1}.
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DR EMBL; NBSK01001411; PLY94337.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6M4A1; -.
DR STRING; 4236.A0A2J6M4A1; -.
DR EnsemblPlants; rna-gnl|WGS:NBSK|LSAT_7X97701_mrna; cds-PLY94337.1; gene-LSAT_7X97701.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_7X97701_mrna; cds-PLY94337.1; gene-LSAT_7X97701.
DR GO; GO:0005777; C:peroxisome; IBA:GO_Central.
DR GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IBA:GO_Central.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IBA:GO_Central.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR23309; 3-HYDROXYACYL-COA DEHYROGENASE; 1.
DR PANTHER; PTHR23309:SF40; ENOYL-COA HYDRATASE_ISOMERASE FAMILY-RELATED; 1.
DR Pfam; PF02737; 3HCDH_N; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE 3: Inferred from homology;
FT DOMAIN 116..199
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
SQ SEQUENCE 223 AA; 23693 MW; D5ED0BAE53721E18 CRC64;
MEDAKKPIVA AVQGLALGGG LELAMGCHAC VTAPRAQLGL PELSLGVMLG LGGTQRLPRL
LGLSKEIDMM LEVKVFNELV VSDTSKGLVH IFFAQRAISK VPKVTDVGLK PRSVKKVVVI
GGGLMWSGIA TALILCNIKV VLKEVNSESL QKGIKTIEAN VKGLVIRKKL PQGQGEKALS
LVNGVLDYSQ FKDVDMVIEG GRDVEVFGSP TEKAILQWGV KVS
//
