ID   A0A2J6MNN3_9BURK        Unreviewed;       421 AA.
AC   A0A2J6MNN3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:PLZ01209.1};
GN   ORFNames=CY652_16810 {ECO:0000313|EMBL:PLZ01209.1};
OS   Burkholderia sp. WAC0059.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=2066022 {ECO:0000313|EMBL:PLZ01209.1, ECO:0000313|Proteomes:UP000243676};
RN   [1] {ECO:0000313|EMBL:PLZ01209.1, ECO:0000313|Proteomes:UP000243676}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WAC0059 {ECO:0000313|EMBL:PLZ01209.1,
RC   ECO:0000313|Proteomes:UP000243676};
RA   Cho S.-T., Yang Y., Chen C.-L., Wang T.-F., Kuo C.-H.;
RT   "Genome Sequence of Burkholderia sp. WAC0059.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RsmB/NOP family. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PLZ01209.1}.
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DR   EMBL; PNEO01000016; PLZ01209.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2J6MNN3; -.
DR   OrthoDB; 9810297at2; -.
DR   Proteomes; UP000243676; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR   InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR   InterPro; IPR023267; RCMT.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR22807:SF77; SUN PROTEIN; 1.
DR   Pfam; PF01189; Methyltr_RsmB-F; 1.
DR   PRINTS; PR02008; RCMTFAMILY.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW   ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000243676};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU01023};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01023};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU01023}.
FT   DOMAIN          141..418
FT                   /note="SAM-dependent MTase RsmB/NOP-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51686"
FT   ACT_SITE        355
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         255
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         282
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         302
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ   SEQUENCE   421 AA;  45314 MW;  9F7A9E859F447839 CRC64;
     MRLHGFLIGQ TETLLAEVLR FDGPADATTS RFFRAHPKLG HGERGVIAEA VFAVLRRRME
     FAHLAESGVG SPTRRLALLG LMQTAGRAAV RPFVTDAEAG WLEHVSKIDP ASLPARVQMN
     LPEWIVRALE TRFDAAELVR LAAALNYPAP LDLRANPLKA GREELLAALA AAGIEAGATP
     FAPLGVRVVG KPALSKLDAF TNGWFEVQDE GSQLLCSLVA PRRGEMIVDF CAGAGGKTLA
     LGAAMRSTGR LYAFDVSEKR LAKLKPRLAR SGLSNVNPVL IDSEHDAKIK RLAGKIDRVL
     VDAPCSGLGT LRRNPDLKWR QTPESVAELA PKQASILASA ARLVKPGGRL VYATCSILAA
     ENEAVVEQFL AAHPDFATVS AREVLAAQRI DLDTGDYLSL WPHRHATDGF FAAVLERRGT
     P
//