ID A0A2J6MWE4_9BURK Unreviewed; 390 AA.
AC A0A2J6MWE4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:PLZ03889.1};
GN ORFNames=CY652_02630 {ECO:0000313|EMBL:PLZ03889.1};
OS Burkholderia sp. WAC0059.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=2066022 {ECO:0000313|EMBL:PLZ03889.1, ECO:0000313|Proteomes:UP000243676};
RN [1] {ECO:0000313|EMBL:PLZ03889.1, ECO:0000313|Proteomes:UP000243676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAC0059 {ECO:0000313|EMBL:PLZ03889.1,
RC ECO:0000313|Proteomes:UP000243676};
RA Cho S.-T., Yang Y., Chen C.-L., Wang T.-F., Kuo C.-H.;
RT "Genome Sequence of Burkholderia sp. WAC0059.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLZ03889.1}.
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DR EMBL; PNEO01000002; PLZ03889.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6MWE4; -.
DR OrthoDB; 8770688at2; -.
DR Proteomes; UP000243676; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06273; PBP1_LacI-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000243676};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 59..113
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 63..107
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 390 AA; 42165 MW; 7496AF1F0C850F44 CRC64;
MRLARRQGGV ARRPARYSRR RAGAARAPRD DGAGWTLTTE GKATREGKKR APRRKSNAVS
VMDVARAAGV STATVSRVLN GHSTVAPDLQ ARVKEIAEAL GYTPHAAARA LASQRSKTIG
AVIPSLENQN FALGVFALQK RIGEAGYTLL LACSYYDQED ELRQVRALIA DGIAGLMLVG
RSHTPALYEL LEKEQVPFVN GWTVDHAHPY VGFDNVAVGR RLAEYLLDLG HVHFAMITQM
TQHSDRAADR IVGVRAALQS RGLELRHEHV IEMPHRIIEG QMAMKALMQG PVRPTAIICG
TDLLAIGALA EAREAGIDVP GELSIAGIND VEFSSFTTPP LTTMRLAADE IGARSADYLL
ARIEGRPISS QNIVPTDLIV RGTTGRPQGK
//
