ID A0A2J6Q028_9HELO Unreviewed; 1149 AA.
AC A0A2J6Q028;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=NA56DRAFT_575061 {ECO:0000313|EMBL:PMD19622.1};
OS Hyaloscypha hepaticicola.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Hyaloscyphaceae; Hyaloscypha.
OX NCBI_TaxID=2082293 {ECO:0000313|EMBL:PMD19622.1, ECO:0000313|Proteomes:UP000235672};
RN [1] {ECO:0000313|EMBL:PMD19622.1, ECO:0000313|Proteomes:UP000235672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 7357 {ECO:0000313|EMBL:PMD19622.1,
RC ECO:0000313|Proteomes:UP000235672};
RG DOE Joint Genome Institute;
RA Martino E., Morin E., Grelet G., Kuo A., Kohler A., Daghino S., Barry K.,
RA Choi C., Cichocki N., Clum A., Copeland A., Hainaut M., Haridas S.,
RA Labutti K., Lindquist E., Lipzen A., Khouja H.-R., Murat C., Ohm R.,
RA Olson A., Spatafora J., Veneault-Fourrey C., Henrissat B., Grigoriev I.,
RA Martin F., Perotto S.;
RT "A degradative enzymes factory behind the ericoid mycorrhizal symbiosis.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KZ613488; PMD19622.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J6Q028; -.
DR STRING; 1745343.A0A2J6Q028; -.
DR OrthoDB; 1630at2759; -.
DR Proteomes; UP000235672; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:InterPro.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd09769; Luminal_IRE1; 1.
DR CDD; cd10422; RNase_Ire1; 1.
DR Gene3D; 1.20.1440.180; KEN domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR045133; IRE1/2-like.
DR InterPro; IPR010513; KEN_dom.
DR InterPro; IPR038357; KEN_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR13954; IRE1-RELATED; 1.
DR PANTHER; PTHR13954:SF6; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR Pfam; PF00069; Pkinase; 2.
DR Pfam; PF06479; Ribonuc_2-5A; 1.
DR SMART; SM00580; PUG; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS51392; KEN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022527};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000235672};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..1149
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014433183"
FT DOMAIN 715..1011
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1014..1146
FT /note="KEN"
FT /evidence="ECO:0000259|PROSITE:PS51392"
FT REGION 575..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..609
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..650
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..673
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1149 AA; 128001 MW; 142F6B5B9A68ED80 CRC64;
MPRRRPPREG PVVNNFFLFA AAIFFLPWLV EAQQQQRPAV QQRHESPHES LDLEASHTLE
VTKIPHQVET PLTHNRRKNT LSVTNGPAKN DASAIATLAP APSAVAAPFS RLPGTSGLSS
PHTARSLEDW EVEDFVLLAT VDGKLHARDR KTGKEKWSLE YHKPMVEINQ NRSNPTPIDE
EYDPVSIDDY LWIVEPSRDG ALYIYKPGGP NPGLVNTNLT MKYLVEEMSG YVSQDPPITY
IGGKNTNIIT VDANSGKILS FFGQEGAFLN DEKCVASNGP VDSKEECPKT STLTVGRTEY
WVKIAGNDGH HIATLTFSEW TPNNFDTDLL RQYHSTLDGK YIYTSHDGGV FGFDHNRDSP
DEPGRLFTHK FTSPVVRVFD VAKPWNGGRE ADLVILPQPS PPHREDVVTA SHRAGSIFLN
HTESGSWYAL SGKTYPLAVQ GIRPAQCSQH GWLQHRPQWD LTNGQQLHEA LVGLHSIDNG
RWEPLLSISG PMDDNQTVDP ISNNTPALVE EQGFFPPVRQ WPSLAAKYGR DTVQNPLLIV
MLVVMIWSYQ KQIKSWVHRT GEKFMKSYSV EAEDKTLPEA DDAPNVAEKD ELKISSVDGA
DEAPEKAEKT EAVLNPVAPR PDSPDEESPP PPGKEKKKAH RGRRGGVKHK KGRAGSTDGG
SQDGSTPKTQ PTIDDAVKDA QNMGPQTKLE PDIITVTSDP QEVSGPIIKI ASLEVNTEKL
IGTGSNGTMV FEGKFDGREV AVKRMLIQFF DIASQETKLL RESDDHPNVI RYFAQQAAAG
FLYIALELCP ASLADVIDKP MKYQEIAQAG EKDLPNVLYQ ITNGLSHLHS LRIVHRDLKP
QNILVAMGKD GKPRLLVSDF GLCKKLEGEQ SSFRATTAHA AGTSGWRAPE LLLDDDAKDG
HHAIVDASTD GGSGPVVLGA ENLPNRRATR AIDIFSLGLV FFYVLTKGSH PFDCGDRFMR
EVNIRKGSYD LTLLEVLGDY AYEAKDLISS MLARDPKQRP QAHQVMAHPF FWSPKKRLNF
LCDVSDHFEK EKRDPPTAAL TELESYAPSV CGSDFLKLLG KEFVESMGKQ RKYTGTRLLD
LLRALRNKRN HYEDMSDKLK KDVGPLPDGY LSFWTRRFPN LLITCWNVVY DVQWDETDRF
REYYLPAGL
//
