ID   A0A2J6QG32_9HELO        Unreviewed;      1333 AA.
AC   A0A2J6QG32;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=5-oxoprolinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=NA56DRAFT_642278 {ECO:0000313|EMBL:PMD25233.1};
OS   Hyaloscypha hepaticicola.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Hyaloscyphaceae; Hyaloscypha.
OX   NCBI_TaxID=2082293 {ECO:0000313|EMBL:PMD25233.1, ECO:0000313|Proteomes:UP000235672};
RN   [1] {ECO:0000313|EMBL:PMD25233.1, ECO:0000313|Proteomes:UP000235672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 7357 {ECO:0000313|EMBL:PMD25233.1,
RC   ECO:0000313|Proteomes:UP000235672};
RG   DOE Joint Genome Institute;
RA   Martino E., Morin E., Grelet G., Kuo A., Kohler A., Daghino S., Barry K.,
RA   Choi C., Cichocki N., Clum A., Copeland A., Hainaut M., Haridas S.,
RA   Labutti K., Lindquist E., Lipzen A., Khouja H.-R., Murat C., Ohm R.,
RA   Olson A., Spatafora J., Veneault-Fourrey C., Henrissat B., Grigoriev I.,
RA   Martin F., Perotto S.;
RT   "A degradative enzymes factory behind the ericoid mycorrhizal symbiosis.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
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DR   EMBL; KZ613470; PMD25233.1; -; Genomic_DNA.
DR   STRING; 1745343.A0A2J6QG32; -.
DR   OrthoDB; 674at2759; -.
DR   Proteomes; UP000235672; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000235672}.
FT   DOMAIN          16..201
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          221..525
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          536..719
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          747..1300
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
FT   REGION          1300..1333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1301..1323
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1333 AA;  145919 MW;  F427A512B5B62FE7 CRC64;
     MSKLPETSCI EQLLTYPSPL EGIRRLMSKF LGKEIPRGRP LDTSKIESIR MGTTVATNAL
     LERKGEKIAM VVTKGFKDCL EIGNQSRPKI FDLAIRKPDV LYEKVVEIDE RVTLEDYAED
     PERNITKVET RDSKNGAADQ HLVRGLSSEA VRILQRPEEE IIRKQLKEVY DQGIRSIAVC
     LMHGYTFPDH EALVGKLARD IGFKHVSLSH ELMPMIKLVP RATSACADAY LTPAIKKYIA
     GFQKGFEGGL GTESVKKESG EKGARCEFMQ SDGGLVDVDN FSGLKAILSG PAGGVVGYAL
     TSYDSETRTP VIGFDMGGTS TDVSRYGGRY EHVFETTTAG VTIQSPQLDI NTVAAGGGSR
     LFFRNGLFVV GPESAGAHPG PGCYRKGGPA TVTDANLFLG RLLPDFFPKI FGKNENEGLD
     VQASEKLLQE LAEQINKENG KNMSADEVAY GFLTVANETM TRPIRSLTEA KGHDTSKHRL
     ATFGGAGGQH AVAIAERLGI RQILVHRYSS VLSAYGMALA DVVDERQEPD SKVWADKGDA
     KELLKKKIEE LKQKSKVALQ DQGFDEKSIV YEEYLNMRYR GTESALMIVK PEKEDVEKEF
     EGDEWAFGKA FVKQHQQEFG FTLPDRDIIV DDVRVRGIGK SFEGLGKTVD QQLKDIVPKD
     LKSGDKEYKR SHVYFEGGRQ DTPIYKLEDL SIGDRIKGPA IVADGTQTIV VTPGASALII
     ETHVVINIGE KELTDSFSKP DTTKEVDPIM LSIFAHRFMA IAEQMGRALQ KTSVSTNVKE
     RLDYSCALFD STGGLVANAP HLPVHLGSMS TCVKRQAEIW RGKLVKGDVV VSNHPEYGGT
     HLPDITVVTP AFDKSGEKIL FYVASRAHHA DIGGILPGSM PPHSRELYQE GAAIKSEKLV
     SAGRFNEERI TELLLTEPAK YKGCSGTRCL ADNLSDLKAQ ISSNMKGITL INDLIEEYGE
     DVVNFYMVNI QNNAELSVRN LLKDVSKRFE GQDLSAVDYM DDGSPIKLKI TIDAEKGEAV
     FDFVGTGPEV YGNTNAPQAV TYSAIIYCLR CLISEDIPLN QGCLKPIKVL IPPKSFLSPS
     DKAAVVGGNV LTSQRVTDVI LKAFQACAAS QGDCNNLTFG FGGNIEGEKD IKGFGYYETI
     AGGSGAGRHW DGTNGVHTHM TNTRITDAEV FERRYPVLLR EFSLRAGSGG AGKHRGGDGV
     IRDIEFRIPV QVSILSERRV YHPYGLAGGE DAQCGLNIWV RKVETSNPER SDKMLNGSNE
     KLDDAVFEER CINLGGKNTA AMKAGERIII CTPGGGGWGK VGDKKETKEM VQDPKHSWRG
     GSHATREELA LQA
//