ID   A0A2J6TMJ7_9HELO        Unreviewed;       421 AA.
AC   A0A2J6TMJ7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=S-adenosyl-L-methionine-dependent methyltransferase {ECO:0000313|EMBL:PMD64241.1};
GN   ORFNames=K444DRAFT_660587 {ECO:0000313|EMBL:PMD64241.1};
OS   Hyaloscypha bicolor E.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Hyaloscyphaceae; Hyaloscypha; Hyaloscypha bicolor.
OX   NCBI_TaxID=1095630 {ECO:0000313|EMBL:PMD64241.1, ECO:0000313|Proteomes:UP000235371};
RN   [1] {ECO:0000313|EMBL:PMD64241.1, ECO:0000313|Proteomes:UP000235371}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E {ECO:0000313|EMBL:PMD64241.1,
RC   ECO:0000313|Proteomes:UP000235371};
RG   DOE Joint Genome Institute;
RA   Martino E., Morin E., Grelet G., Kuo A., Kohler A., Daghino S., Barry K.,
RA   Choi C., Cichocki N., Clum A., Copeland A., Hainaut M., Haridas S.,
RA   Labutti K., Lindquist E., Lipzen A., Khouja H.-R., Murat C., Ohm R.,
RA   Olson A., Spatafora J., Veneault-Fourrey C., Henrissat B., Grigoriev I.,
RA   Martin F., Perotto S.;
RT   "A degradative enzymes factory behind the ericoid mycorrhizal symbiosis.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. Cation-independent O-methyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00038277}.
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DR   EMBL; KZ613769; PMD64241.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2J6TMJ7; -.
DR   InParanoid; A0A2J6TMJ7; -.
DR   OrthoDB; 1067404at2759; -.
DR   Proteomes; UP000235371; Unassembled WGS sequence.
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR016461; COMT-like.
DR   InterPro; IPR001077; O_MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43712:SF20; O-METHYLTRANSFERASE ASQN; 1.
DR   PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR   Pfam; PF00891; Methyltransf_2; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51683; SAM_OMT_II; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:PMD64241.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000235371};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000313|EMBL:PMD64241.1}.
FT   DOMAIN          196..400
FT                   /note="O-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00891"
SQ   SEQUENCE   421 AA;  46432 MW;  8875AAA74A4344A9 CRC64;
     MSSLERASGQ GPPPFEPPVE ILSSLSDSIQ AALARYAAAS TAQEKTSALK AIQSTSSKLS
     TATSPIQQRF MELNARPYLN VTVRIALELN LFEAIPAFGH LTLKELAKEI NASEEFIFRL
     VRVLGAFEIL EVTYPPPNHP PNHLMSLAHT PMSRLLISPA AKASFRNHFE ILLPAHLSSA
     PGYYHKYGFK SPEDLKNVPF TFAHGAQDEG FFDLLVKDEN KFKLFNDAME IMAVLGMKPL
     GSLFAFDKLV SNEDGVALVD IGGGKGQMLK AIQEAYPHMK GKLVLEDLKA VLDGGVIVSE
     DVKLQTYDFF KEVQPIKGSN YFLKSIIHDW PDEACLQILS NLAPAMRGHP HSKLLICELV
     LPDQYPEPAK VVRDIMMLFI GGQERNLFQW HGLLQRAGFK IVNVHGAGGD NSSIIEAVLD
     E
//