ID A0A2J7PS68_9NEOP Unreviewed; 1340 AA.
AC A0A2J7PS68;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Signal-induced proliferation-associated 1-like protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=B7P43_G09603 {ECO:0000313|EMBL:PNF19182.1};
OS Cryptotermes secundus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Kalotermitidae; Cryptotermitinae; Cryptotermes.
OX NCBI_TaxID=105785 {ECO:0000313|EMBL:PNF19182.1, ECO:0000313|Proteomes:UP000235965};
RN [1] {ECO:0000313|EMBL:PNF19182.1, ECO:0000313|Proteomes:UP000235965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole body {ECO:0000313|EMBL:PNF19182.1};
RA Harrison M.C., Jongepier E., Robertson H.M., Arning N., Bitard-Feildel T.,
RA Chao H., Childers C.P., Dinh H., Doddapaneni H., Dugan S., Gowin J.,
RA Greiner C., Han Y., Hu H., Hughes D.S.T., Huylmans A.-K., Kemena C.,
RA Kremer L.P.M., Lee S.L., Lopez-Ezquerra A., Mallet L., Monroy-Kuhn J.M.,
RA Moser A., Murali S.C., Muzny D.M., Otani S., Piulachs M.-D., Poelchau M.,
RA Qu J., Schaub F., Wada-Katsumata A., Worley K.C., Xie Q., Ylla G.,
RA Poulsen M., Gibbs R.A., Schal C., Richards S., Belles X., Korb J.,
RA Bornberg-Bauer E.;
RT "Hemimetabolous genomes reveal molecular basis of termite eusociality.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNF19182.1}.
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DR EMBL; NEVH01021938; PNF19182.1; -; Genomic_DNA.
DR STRING; 105785.A0A2J7PS68; -.
DR InParanoid; A0A2J7PS68; -.
DR Proteomes; UP000235965; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15711:SF70; RAP-GAP DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF21022; Rap-GAP_dimer; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000235965}.
FT DOMAIN 254..471
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT DOMAIN 610..674
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 25..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 729..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 801..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 940..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1060..1090
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1112..1157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1174..1196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1277..1328
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 742..785
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 943..957
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 965..1007
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1020..1039
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1070..1090
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1124..1140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1141..1157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1340 AA; 147073 MW; 1D2E89E6D067AD3A CRC64;
MTANLGYAAK LRGLLLARRR NTTTGASAAS MLGARSATPD GGDSGDEDAG DGRGNDLLES
CPFFRNEIGG EEERVVSLTR GQSPQNAQRR PLHRPPMAYG VSVLEFPPGE THWQHGTCPY
QRNPRAIESV DQGALYYRNH FYGQDHQNWF GMDENLGPVA VSIRRERIER QNDPNSANSS
SAPPSHAYHY RLLIRTSELF TLRGSVLEEA IPNLKTSNSN KTLNTKEVLE YVAPEIQLSC
LRLGVASQQT EDQLLKLDEQ GLTNHYKVGI MYCRAGQASE EEMYNNEEAG PAFHEFLDAI
GQRVRLKGFD KYRAGLDNKT DSTGLYSVYS QYQDCEIMFH VSTLLPFTPN NRQQLLRKRH
IGNDIVTIVF QEPGAQPFTP KNIRSQFQHV FIVVRAINPC SDNTQYRVAV SRSKEVPVFG
PPIHEGATFP KSKAFSDFLL AKVINAENAA HRSEKFATMA TRTRQEYLKD LANNYSSTTV
VDQGQKFSIM SFSSKKKERV RPRFLPDALQ RGAISWQVVL DDSGQAALVD CYLGISTDTL
VLIEERSREI VFVMPCKAIL GWSTQTNSLR VYHHQGECTT LHMREGGDRD ELMEIVVRLR
AVTGGCVAQE LSLRRNPMGQ LGFHVQPDGV VTQVESLGLA WQAGLRHGAR LVEICKVAVS
TLSHDQMVDL LKTSMMVTVT VIPPLPDGSP RRGCTLQNCR YTLNNYEGDY ENVSGRGGDD
KMGRNVAAAV PGKHRRRYER SFSPPQSSSS SGYGTGSSSK SFADPRFPAN SEGTMTSSSS
GHSSDDQWYE LLEPAEPDVS VVVRESPPPP LPARLGSGGG SAFQQVPPKQ SLHGGKLPVQ
ASHSLPLNPL GNYSLPPSAP TRYNPGGDYE SSAHHDFKLG EKVTCLKSSG GEARPVPRPT
LDYLVTRTPK ISDYSGHQHA AVEVTKSSSL PPDCATLRGL AVSDGHSTDT SSASERLFGA
PSEDELSAGS SNVSPRLRRS TKHFQSNGAG GGTLTPSSSG SRNQSPRPRD TGEARLRPGV
TPRNSSNRNS ANLTASTLQE DLMRLINPDY MAERDEKISK EPAGNGAVAG KIHSSSNGSS
SNGGNVNDAA INNRSRSREN LCNSNMNGPS LSVLPACQSA PDPDLHTREQ HGRDQLQHAR
DQHANSSSSN VTAEHGSSGE VILTLARPAT VISNASTASS PAPSENKLTK EERLSPRVTK
LAEPLLLPDA REMDWPSLVD TATRAMMQVP HDEPVPEAAR NGESLGHWVD DVAERLGLDA
TVANIKNNSL VTGGRRMTEL QSHLAQLEAR VARETRRRQS LEEEVRRLRD ENRRLQEESQ
AAAQQLRRFT EWFFQTIDRQ
//
