ID A0A2J7PSG2_9NEOP Unreviewed; 647 AA.
AC A0A2J7PSG2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=phosphoenolpyruvate carboxykinase (GTP) {ECO:0000256|ARBA:ARBA00012306};
DE EC=4.1.1.32 {ECO:0000256|ARBA:ARBA00012306};
GN Name=Pepck {ECO:0000313|EMBL:PNF19275.1};
GN ORFNames=B7P43_G07505 {ECO:0000313|EMBL:PNF19275.1};
OS Cryptotermes secundus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Kalotermitidae; Cryptotermitinae; Cryptotermes.
OX NCBI_TaxID=105785 {ECO:0000313|EMBL:PNF19275.1, ECO:0000313|Proteomes:UP000235965};
RN [1] {ECO:0000313|EMBL:PNF19275.1, ECO:0000313|Proteomes:UP000235965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole body {ECO:0000313|EMBL:PNF19275.1};
RA Harrison M.C., Jongepier E., Robertson H.M., Arning N., Bitard-Feildel T.,
RA Chao H., Childers C.P., Dinh H., Doddapaneni H., Dugan S., Gowin J.,
RA Greiner C., Han Y., Hu H., Hughes D.S.T., Huylmans A.-K., Kemena C.,
RA Kremer L.P.M., Lee S.L., Lopez-Ezquerra A., Mallet L., Monroy-Kuhn J.M.,
RA Moser A., Murali S.C., Muzny D.M., Otani S., Piulachs M.-D., Poelchau M.,
RA Qu J., Schaub F., Wada-Katsumata A., Worley K.C., Xie Q., Ylla G.,
RA Poulsen M., Gibbs R.A., Schal C., Richards S., Belles X., Korb J.,
RA Bornberg-Bauer E.;
RT "Hemimetabolous genomes reveal molecular basis of termite eusociality.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase [GTP]
CC family. {ECO:0000256|ARBA:ARBA00005796}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNF19275.1}.
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DR EMBL; NEVH01021928; PNF19275.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J7PSG2; -.
DR STRING; 105785.A0A2J7PSG2; -.
DR InParanoid; A0A2J7PSG2; -.
DR OrthoDB; 5471652at2759; -.
DR Proteomes; UP000235965; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004613; F:phosphoenolpyruvate carboxykinase (GTP) activity; IEA:UniProtKB-EC.
DR GO; GO:0043648; P:dicarboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:0006094; P:gluconeogenesis; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00819; PEPCK_GTP; 1.
DR Gene3D; 3.90.228.20; -; 1.
DR Gene3D; 3.40.449.10; Phosphoenolpyruvate Carboxykinase, domain 1; 1.
DR Gene3D; 2.170.8.10; Phosphoenolpyruvate Carboxykinase, domain 2; 1.
DR HAMAP; MF_00452; PEPCK_GTP; 1.
DR InterPro; IPR018091; PEP_carboxykin_GTP_CS.
DR InterPro; IPR013035; PEP_carboxykinase_C.
DR InterPro; IPR008209; PEP_carboxykinase_GTP.
DR InterPro; IPR035077; PEP_carboxykinase_GTP_C.
DR InterPro; IPR035078; PEP_carboxykinase_GTP_N.
DR InterPro; IPR008210; PEP_carboxykinase_N.
DR PANTHER; PTHR11561; PHOSPHOENOLPYRUVATE CARBOXYKINASE; 1.
DR PANTHER; PTHR11561:SF0; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP)-RELATED; 1.
DR Pfam; PF00821; PEPCK_GTP; 1.
DR Pfam; PF17297; PEPCK_N; 1.
DR PIRSF; PIRSF001348; PEP_carboxykinase_GTP; 1.
DR SUPFAM; SSF68923; PEP carboxykinase N-terminal domain; 1.
DR SUPFAM; SSF53795; PEP carboxykinase-like; 1.
DR PROSITE; PS00505; PEPCK_GTP; 1.
PE 3: Inferred from homology;
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Kinase {ECO:0000313|EMBL:PNF19275.1};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Pyruvate {ECO:0000313|EMBL:PNF19275.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000235965};
KW Transferase {ECO:0000313|EMBL:PNF19275.1}.
FT DOMAIN 55..282
FT /note="Phosphoenolpyruvate carboxykinase GTP-utilising N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF17297"
FT DOMAIN 286..643
FT /note="Phosphoenolpyruvate carboxykinase C-terminal P-loop"
FT /evidence="ECO:0000259|Pfam:PF00821"
SQ SEQUENCE 647 AA; 71903 MW; D3B06667424B79AB CRC64;
MPDVIEKEQY TSYVSSVSRY TKLLSQPNVG LYNHLRGITI SHGDLHSLSP KVRTYVEENI
SLCEPSSVHI CDGSEAENSL LLRLMLQQGT IKPLPKYDNC WLAQTNPADV ARVESRTFIC
TDDRHDTIPT PKAGVKGTLG NWMSPEDMSN AIRHRFPGCM RGRTMYVIPF SMGPVGSPLS
KIGIEITDSP YVVSSMRIMT RVGVPVLQAL AQGAEFVKCL HSVGSPQNLE AVNHGWPCDP
ERTIILHRPE KNEIVSYGSG YGGNSLLGKK CFALRIGSTI AKREGWLAEH MLILGITNPA
GRKRYIAAAF PSACGKTNLA MMCPSLPGYK VECVGDDIAW MKFDSNGQLR AINPENGFFG
VAPGTSSKTN PNAMKTVFRN TLFTNVAATS DGGVFWEGLE DELAPGVTIT DWQGKPWDRS
TPAAHPNSRF CSPASQCPII DPSWEDPEGV PIDAILFGGR RPVGVPLVYE AYNWHHGVFI
GAAMRSESTA AAEHKGKIIM HDPFAMRPFF GYNFGHYLEH WLNMENTFGR KLPKVFHVNW
FRKDAQGKFL WPGFGENSRV LDWIFRRIDN EEIAQPTPVG YVPKTDCLNL DGLSETINMT
ELFSLPKDFW LQEVTDIEQY FSEQVGADLP VAIAEELSAL RQRLLNM
//
