ID A0A2J7QPY6_9NEOP Unreviewed; 1014 AA.
AC A0A2J7QPY6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Replication factor C subunit 1 {ECO:0000256|ARBA:ARBA00020401, ECO:0000256|PIRNR:PIRNR036578};
GN Name=Gnf1 {ECO:0000313|EMBL:PNF30645.1};
GN ORFNames=B7P43_G06179 {ECO:0000313|EMBL:PNF30645.1};
OS Cryptotermes secundus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Kalotermitidae; Cryptotermitinae; Cryptotermes.
OX NCBI_TaxID=105785 {ECO:0000313|EMBL:PNF30645.1, ECO:0000313|Proteomes:UP000235965};
RN [1] {ECO:0000313|EMBL:PNF30645.1, ECO:0000313|Proteomes:UP000235965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole body {ECO:0000313|EMBL:PNF30645.1};
RA Harrison M.C., Jongepier E., Robertson H.M., Arning N., Bitard-Feildel T.,
RA Chao H., Childers C.P., Dinh H., Doddapaneni H., Dugan S., Gowin J.,
RA Greiner C., Han Y., Hu H., Hughes D.S.T., Huylmans A.-K., Kemena C.,
RA Kremer L.P.M., Lee S.L., Lopez-Ezquerra A., Mallet L., Monroy-Kuhn J.M.,
RA Moser A., Murali S.C., Muzny D.M., Otani S., Piulachs M.-D., Poelchau M.,
RA Qu J., Schaub F., Wada-Katsumata A., Worley K.C., Xie Q., Ylla G.,
RA Poulsen M., Gibbs R.A., Schal C., Richards S., Belles X., Korb J.,
RA Bornberg-Bauer E.;
RT "Hemimetabolous genomes reveal molecular basis of termite eusociality.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036578}.
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116, ECO:0000256|PIRNR:PIRNR036578}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNF30645.1}.
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DR EMBL; NEVH01012087; PNF30645.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J7QPY6; -.
DR STRING; 105785.A0A2J7QPY6; -.
DR InParanoid; A0A2J7QPY6; -.
DR OrthoDB; 6297at2759; -.
DR Proteomes; UP000235965; Unassembled WGS sequence.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd17752; BRCT_RFC1; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF6; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR036578};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR036578};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR036578}; Nucleus {ECO:0000256|PIRNR:PIRNR036578};
KW Reference proteome {ECO:0000313|Proteomes:UP000235965}.
FT DOMAIN 284..374
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 945..1014
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..202
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..968
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 993..1014
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1014 AA; 114455 MW; 3A8E6702A7320AA4 CRC64;
MSHDIRSYFP PKAGSEAKGK CKEMKVNVER RHRKRQLVCI DSDSDEDILP SQVKKHERKS
GISVSCVRGV TQKNSKSISK PELKPIDVAD VFGNSQIKRT ASKKDEVKKV MKNVTPQLEN
LHSDSEFVGT LQELDERKNF CKKENEITPV KEKQKHALHT SEFSKSALDS YKIPRNAMKE
TPNKTDIKLL AQKEESRDKE TTSLISQPET SPDLPKKIKG NEYLSTENGT QQEKAVRSPA
SVKRCDISSD EDVYERKRQH AMQYQRYLQR EGPKNPGGKE VPQGRPGCLS GLVFVVTGVL
ETIDREETSS LIKQCGGRVT SSVSRNTNYL VVGEEPGPAK IEKAAKLNTP HLTEDELFAL
IRARSCLPDT ERLSKDSEEV IKKDEKIKHK DNLSRNDITH GTRIETSKSI KKNIKKEETE
MPVLEKQDIS LSPPSARNTT FQRHSLWADK YKPVSTKHII GQQGDRSNVK KLIKWLQSWH
SNHSGKKKLV RPSPWAKDET GSYFKAALLS GPPGVGKTTT AHLVCEELGF DVVEFNASDT
RSKKLLHEEV SELLNNKSLS GYFQGAAGRK PTENHVLIMD EVDGMAGNED RGGMQELIQL
IKSSRVPVIC MCNDRHHPKI RSLTNYCFDL QFSRPSVKQI GGAMMSICFK EGIKMSPETL
NDIITGTNHD VRQVLHHLSV WSVKDKQLSF ENIKEESLKA KKDVKLGPWD VVKKVFSADV
HKSMSIHDKS DLFFHDYSLG PLFVQENYLG VMPHKSRNNR KRHLELVAQT AESLSSGDMV
EKTIRSKSAW SLLPAQAIFS SVLPGDLLEG HFTCQINFPA WLGKNSRRSK FQRLLQELHG
HMRLNISGSK EAVNLDYMTH LRDAISGPLI KDGVDGVPAT LHVMQDYYLL REDIDSLMEL
SLWPNQKDPM SLVDSKVKAA LTHRFNKGGI MTPYSIVKIK NSASKSSQDL EFDGDEQDVG
EEEEEEEGIT RDAMIKVKKR NTTTQNPAPG RSGAKRRKVD NKEVRKKNDK HERK
//
