ID A0A2J7QQ85_9NEOP Unreviewed; 986 AA.
AC A0A2J7QQ85;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Transient receptor potential cation channel trpm {ECO:0008006|Google:ProtNLM};
GN ORFNames=B7P43_G06170 {ECO:0000313|EMBL:PNF30754.1};
OS Cryptotermes secundus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Kalotermitidae; Cryptotermitinae; Cryptotermes.
OX NCBI_TaxID=105785 {ECO:0000313|EMBL:PNF30754.1, ECO:0000313|Proteomes:UP000235965};
RN [1] {ECO:0000313|EMBL:PNF30754.1, ECO:0000313|Proteomes:UP000235965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole body {ECO:0000313|EMBL:PNF30754.1};
RA Harrison M.C., Jongepier E., Robertson H.M., Arning N., Bitard-Feildel T.,
RA Chao H., Childers C.P., Dinh H., Doddapaneni H., Dugan S., Gowin J.,
RA Greiner C., Han Y., Hu H., Hughes D.S.T., Huylmans A.-K., Kemena C.,
RA Kremer L.P.M., Lee S.L., Lopez-Ezquerra A., Mallet L., Monroy-Kuhn J.M.,
RA Moser A., Murali S.C., Muzny D.M., Otani S., Piulachs M.-D., Poelchau M.,
RA Qu J., Schaub F., Wada-Katsumata A., Worley K.C., Xie Q., Ylla G.,
RA Poulsen M., Gibbs R.A., Schal C., Richards S., Belles X., Korb J.,
RA Bornberg-Bauer E.;
RT "Hemimetabolous genomes reveal molecular basis of termite eusociality.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNF30754.1}.
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DR EMBL; NEVH01012087; PNF30754.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J7QQ85; -.
DR STRING; 105785.A0A2J7QQ85; -.
DR InParanoid; A0A2J7QQ85; -.
DR Proteomes; UP000235965; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:UniProt.
DR GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR Gene3D; 1.20.5.1010; TRPM, tetramerisation domain; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR032415; TRPM_tetra.
DR InterPro; IPR037162; TRPM_tetra_sf.
DR PANTHER; PTHR13800:SF1; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL TRPM; 1.
DR PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF16519; TRPM_tetra; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000235965};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 155..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 162..394
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 485..540
FT /note="TRPM tetramerisation"
FT /evidence="ECO:0000259|Pfam:PF16519"
FT REGION 53..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 837..860
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 488..515
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 669..716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..745
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 986 AA; 113269 MW; B833DBB6F1C28473 CRC64;
MGGLRTRKNT NLKVILGLLC PFYIAKLEFK SKEELQLMPQ TEEEHLIGLE EENESIEGQP
TDTNCNLEPD AEKKPRKFSI RSNPTSQQGI KALISHENYA MRNTVVQENG KVVTECDDMN
QHFHFPLDYF EVKNNRPLRL RKKLYEFYTA PITKFWGHSI AYIVFLVTFT YVVLVKMDMK
PSWQELYTIA YICTLAFEKV REIVSSEPVA VSHKLSVWAW NMWNPCDAAA IIFFLIGLCL
RLRLSSMQVG RLIFCVDIVY WYLRILKILG VNKYLGPLVT MMGKMVKDMI YFVVLLLVVL
MSFGVCRQAI LNPDKEPSWS LVRDIFFKPY FMLYGEVFAD SIDPPCGDDP GLEKCQMGRW
ITAVEMAVYL LVANILLINL LIAVFNNIFN EVNAISHEVW MFQRFTVVME YEEKPVLPPP
LIVLCHVFLL LKYCHRKVRG VRELYDNALK LFLDHEDLER LYDFEEECVE GYFREQETKL
HVSNDECIRN TADRVDNMYQ KIEDINQKEN KLNSALQGVE FRMRKLEDLT DQTLSHLAVI
HRFMATHVQD PLPMSDLPDV RLGTERIRLS SDRSDDQKAL SETSDHAEKV HLLPMLSRDR
RRPTRSLTEV RPDSFLLGES FHVRLDDDVQ TTDKFIPMFE KAEQEGEEEK EEDGEISDLS
HTIRKRIPHQ LTKQMSMSRN SLSDPVESHS GSNLEGTADI GNNEDNTQSR ILFRGNSSDY
RSERRESSAS SNRKHSLEIG EDSEKGSVMQ RPPALTRRQI SKTHSEPENA TGPNLQDENE
IPRVAVVERS VTWAEPRITV IPPSIRTNPR AMLLAMHSEY TSITDELETV CGLLSPPHTP
RLLSPPRPGE NLPRRTRHTS EMSNPEMALF LEKEHLRDAE ENDYQLMETL MHQHMGQHEE
DAAECSAFFL NVTNETPEFR SRSLHRSSAI EVKDFPTPCT HGPPAIFCTD ADSQQLQIIC
TESGLEEVSG SGADALSLMP TSETTC
//
