ID A0A2J7QQL5_9NEOP Unreviewed; 882 AA.
AC A0A2J7QQL5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Glutamate receptor ionotropic, kainate 2 {ECO:0000313|EMBL:PNF30867.1};
GN Name=GRIK2_6 {ECO:0000313|EMBL:PNF30867.1};
GN ORFNames=B7P43_G06118 {ECO:0000313|EMBL:PNF30867.1};
OS Cryptotermes secundus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Kalotermitidae; Cryptotermitinae; Cryptotermes.
OX NCBI_TaxID=105785 {ECO:0000313|EMBL:PNF30867.1, ECO:0000313|Proteomes:UP000235965};
RN [1] {ECO:0000313|EMBL:PNF30867.1, ECO:0000313|Proteomes:UP000235965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole body {ECO:0000313|EMBL:PNF30867.1};
RA Harrison M.C., Jongepier E., Robertson H.M., Arning N., Bitard-Feildel T.,
RA Chao H., Childers C.P., Dinh H., Doddapaneni H., Dugan S., Gowin J.,
RA Greiner C., Han Y., Hu H., Hughes D.S.T., Huylmans A.-K., Kemena C.,
RA Kremer L.P.M., Lee S.L., Lopez-Ezquerra A., Mallet L., Monroy-Kuhn J.M.,
RA Moser A., Murali S.C., Muzny D.M., Otani S., Piulachs M.-D., Poelchau M.,
RA Qu J., Schaub F., Wada-Katsumata A., Worley K.C., Xie Q., Ylla G.,
RA Poulsen M., Gibbs R.A., Schal C., Richards S., Belles X., Korb J.,
RA Bornberg-Bauer E.;
RT "Hemimetabolous genomes reveal molecular basis of termite eusociality.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNF30867.1}.
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DR EMBL; NEVH01012087; PNF30867.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2J7QQL5; -.
DR Proteomes; UP000235965; Unassembled WGS sequence.
DR GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0007154; P:cell communication; IEA:UniProt.
DR CDD; cd06382; PBP1_iGluR_Kainate; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR001508; Iono_Glu_rcpt_met.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966:SF422; KAINATE-TYPE IONOTROPIC GLUTAMATE RECEPTOR SUBUNIT 1D; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR PRINTS; PR00177; NMDARECEPTOR.
DR SMART; SM00918; Lig_chan-Glu_bd; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00023257};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:PNF30867.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000235965};
KW Signal {ECO:0000256|SAM:SignalP}; Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..882
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014324688"
FT TRANSMEM 555..574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 631..653
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 824..845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 424..795
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DOMAIN 434..499
FT /note="Ionotropic glutamate receptor L-glutamate and
FT glycine-binding"
FT /evidence="ECO:0000259|SMART:SM00918"
SQ SEQUENCE 882 AA; 99192 MW; 85FBEB28E49E2629 CRC64;
MAPCTEMAGR ALLVAVLCCG NLVAALPDVI RIGGLFHPAD DRQEVAFRYA VERINDDRTI
LPRSRLSAQI EKISPQDSFH ASKRVCHLLR SGVAAIFGPQ SGQTASHVQS ICDTMEIPHL
ETRWDYRLRR ESCLVNLYPH PTALSKAYVD LVRAWGWRSF TIIYESNEGL VRLQELLKAH
GPSEFPITVR QLGEGADYRP LLKQIKNSAE SHIVLDCNTE RIYDVLKQAQ QIGMMSDYHS
YLITSLDLHS VDLEEFKYGG TNITALRLVD PEKPELQKVV RNWVYGELRY GRKLDLPPPR
DNLTFIKTET ALMYDAVHLF AKALHDLDSS QRIDIKPLSC DAVDTWPHGY SLINYMKIVE
MQGLTGVIKF DNQGFRSNFV LDIVELSKDG LKKIGTWNST EGVNFTRTYG EAYTQIVESL
QNKTFVVTTI LSSPYCMRKD SSEKLSGNAQ FEGYGLDLVH EISKILGFNY TFKLVPDGRY
GSLNRETKEW DGMMKELLDQ KADIAIADLT ITYDREQAVD FTMPFMNLGI SILYRKPIKQ
PPNLFSFLSP LSLDVWIYMA TAYLGVSVLL FILARFSPYE WDNPHPCNDE PDVLENQFSL
LNSLWFTIGS LMQQGSDIAP KAVSTRMVAG MWWFFTLIMI SSYTANLAAF LTVERMDSPI
ESAEDLAKQT KIKYGALKGG STAAFFRDSN FSTYQRMWSF MESARPSVFT SSNMEGVERV
VKGKGNYAFL MESTSIEYVI ERNCELTQVG GLLDSKGYGI AMPPNSPYRT AISGAVLKLQ
EEGKLHILKT RWWKEKRGGG ACRDDTSKSS SAANELGLAN VGGVFVVLMG GMGVACVIAV
CEFVWKSRKV AMEERLDSFP EQNRVVVQQH QCNGSLLKTS GQ
//
