ID   A0A2J7RC50_9NEOP        Unreviewed;       745 AA.
AC   A0A2J7RC50;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   22-FEB-2023, entry version 14.
DE   RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
GN   ORFNames=B7P43_G07251 {ECO:0000313|EMBL:PNF38412.1};
OS   Cryptotermes secundus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC   Kalotermitidae; Cryptotermitinae; Cryptotermes.
OX   NCBI_TaxID=105785 {ECO:0000313|EMBL:PNF38412.1, ECO:0000313|Proteomes:UP000235965};
RN   [1] {ECO:0000313|EMBL:PNF38412.1, ECO:0000313|Proteomes:UP000235965}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Whole body {ECO:0000313|EMBL:PNF38412.1};
RA   Harrison M.C., Jongepier E., Robertson H.M., Arning N., Bitard-Feildel T.,
RA   Chao H., Childers C.P., Dinh H., Doddapaneni H., Dugan S., Gowin J.,
RA   Greiner C., Han Y., Hu H., Hughes D.S.T., Huylmans A.-K., Kemena C.,
RA   Kremer L.P.M., Lee S.L., Lopez-Ezquerra A., Mallet L., Monroy-Kuhn J.M.,
RA   Moser A., Murali S.C., Muzny D.M., Otani S., Piulachs M.-D., Poelchau M.,
RA   Qu J., Schaub F., Wada-Katsumata A., Worley K.C., Xie Q., Ylla G.,
RA   Poulsen M., Gibbs R.A., Schal C., Richards S., Belles X., Korb J.,
RA   Bornberg-Bauer E.;
RT   "Hemimetabolous genomes reveal molecular basis of termite eusociality.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PNF38412.1}.
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DR   EMBL; NEVH01005887; PNF38412.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2J7RC50; -.
DR   Proteomes; UP000235965; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR   CDD; cd15047; 7tmC_GABA-B-like; 1.
DR   InterPro; IPR002455; GPCR3_GABA-B.
DR   InterPro; IPR017978; GPCR_3_C.
DR   PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR   PANTHER; PTHR10519:SF46; METABOTROPIC GABA-B RECEPTOR SUBTYPE 3, ISOFORM A; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   PRINTS; PR01177; GABAB1RECPTR.
DR   PRINTS; PR01176; GABABRECEPTR.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000235965};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        94..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        216..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          44..251
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
FT   REGION          311..334
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          438..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          720..745
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        725..745
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   745 AA;  81274 MW;  E092339457060175 CRC64;
     MCRYIKLSSP RLNNIAVVGC ILVYTAVILL GLDHATLPTN THFSAVCTAR VYLLSAGFSL
     AFGSMFTKTY RVHRIFTRSH SGVVKNKLLQ DTQLISLICV LLLIDGLIVT LWVIIDPIQR
     HLRNLTLEIS ASDRSVVYQP QVEVCRSQYT HGWLGALYGY KGLLLIVGVY MAWETRHVKI
     PALNDSQYIG MSVYSVVITS AIVVVLANLI SERATLAFVT ITTLILTSTT ATLCLLFLPK
     LHAIFGHADD NGDPIMHSMG LKIEYNTRRF VTDDRRELYY RVEVQNRVYR REIAALDLEI
     GRLKRQLIES PNASSDSMSE GAASKKTDLS PEERGASRKY NVMEMLPSPI VGGGLPLLLL
     SVLPPVIPRA SWPSADHGNL PMRRQVTFSS EPKLDDSVAK QTAEKSAKEQ EYYIICDSQD
     SDTETSGKPG VFSRLKNFLG SRPSSRKTSA ASFSGTSSGG GIASALRVHM GYLAGLVPNS
     NMAAMTSSCN TSIAALNQYG LSGGPSSKEL HPLKSFCGRV GGGSGPIISV TSNDEPEENT
     CLNGGGNSVN RRKFSLGMCL SHKEEKDFGN DERRVSYSSM QKEVMQHQHS QPILSFRERA
     KGSPRFPHRI VPTCSLNALE DRRRSSSSAA AATGYSVNAS GSNPSYLARH HLHVSKQTVG
     GHSHMGGKCR SLEDATSTGV WSSSASAGVS NWKPRASSYS PNCDVWATAE FGIPLSELGN
     SGRCRDKNVP QSVQERDPQC SQVPM
//