ID   A0A2J7REX1_9NEOP        Unreviewed;       363 AA.
AC   A0A2J7REX1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Developmentally-regulated GTP-binding protein 2 {ECO:0000313|EMBL:PNF39376.1};
GN   Name=DRG2 {ECO:0000313|EMBL:PNF39376.1};
GN   ORFNames=B7P43_G13655 {ECO:0000313|EMBL:PNF39376.1};
OS   Cryptotermes secundus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC   Kalotermitidae; Cryptotermitinae; Cryptotermes.
OX   NCBI_TaxID=105785 {ECO:0000313|EMBL:PNF39376.1, ECO:0000313|Proteomes:UP000235965};
RN   [1] {ECO:0000313|EMBL:PNF39376.1, ECO:0000313|Proteomes:UP000235965}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Whole body {ECO:0000313|EMBL:PNF39376.1};
RA   Harrison M.C., Jongepier E., Robertson H.M., Arning N., Bitard-Feildel T.,
RA   Chao H., Childers C.P., Dinh H., Doddapaneni H., Dugan S., Gowin J.,
RA   Greiner C., Han Y., Hu H., Hughes D.S.T., Huylmans A.-K., Kemena C.,
RA   Kremer L.P.M., Lee S.L., Lopez-Ezquerra A., Mallet L., Monroy-Kuhn J.M.,
RA   Moser A., Murali S.C., Muzny D.M., Otani S., Piulachs M.-D., Poelchau M.,
RA   Qu J., Schaub F., Wada-Katsumata A., Worley K.C., Xie Q., Ylla G.,
RA   Poulsen M., Gibbs R.A., Schal C., Richards S., Belles X., Korb J.,
RA   Bornberg-Bauer E.;
RT   "Hemimetabolous genomes reveal molecular basis of termite eusociality.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PNF39376.1}.
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DR   EMBL; NEVH01004429; PNF39376.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2J7REX1; -.
DR   STRING; 105785.A0A2J7REX1; -.
DR   InParanoid; A0A2J7REX1; -.
DR   OrthoDB; 146471at2759; -.
DR   Proteomes; UP000235965; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   CDD; cd01896; DRG; 1.
DR   CDD; cd17231; TGS_DRG2; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   Gene3D; 6.10.140.1070; -; 2.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR045001; DRG.
DR   InterPro; IPR031167; G_OBG.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR031662; GTP-binding_2.
DR   InterPro; IPR006074; GTP1-OBG_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR004095; TGS.
DR   InterPro; IPR012676; TGS-like.
DR   NCBIfam; TIGR00231; small_GTP; 1.
DR   PANTHER; PTHR43127; DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2; 1.
DR   PANTHER; PTHR43127:SF2; DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   Pfam; PF16897; MMR_HSR1_Xtn; 1.
DR   Pfam; PF02824; TGS; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF81271; TGS-like; 1.
DR   PROSITE; PS51710; G_OBG; 1.
DR   PROSITE; PS00905; GTP1_OBG; 1.
DR   PROSITE; PS51880; TGS; 1.
PE   4: Predicted;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000235965}.
FT   DOMAIN          62..287
FT                   /note="OBG-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51710"
FT   DOMAIN          287..362
FT                   /note="TGS"
FT                   /evidence="ECO:0000259|PROSITE:PS51880"
SQ   SEQUENCE   363 AA;  40721 MW;  8AE1E12F0EA5E495 CRC64;
     MGILEKISEI EKEIARTQKN KATEYHLGLL KAKLAKYRSQ LLEPPKKSEK GEGFDVLKSG
     DARVALIGFP SVGKSTLLST LTATESEAAS YEFTTLTCIP GVIEYKGANI QLLDLPGIIE
     GASQGKGRGR QVIAVARTAD LVLMMLDATK QDVQRGLLEK ELESVGIRLN KRKPNIYFKV
     KKGGGLSFNS TCPLSQVDEK LVQMILHEYK IFNAEVLFRE DCTADELIDV ISANRVYLPC
     LYVYNKIDQI SIEEVDRIAR QPNSVVVSCN MKLNLDYLLE QLWEYLSLIR VYTKKPGQPP
     DFEDSLILRR GVTVEHVCHA IHRTLAAAFK YALVWGTSTK YSPQRVGLHH VMHDEDVIQV
     VKK
//