ID A0A2J8CZ60_VERDA Unreviewed; 432 AA.
AC A0A2J8CZ60;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=2-dehydropantoate 2-reductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BJF96_g1587 {ECO:0000313|EMBL:PNH35086.1}, VDGE_10302
GN {ECO:0000313|EMBL:RXG43161.1};
OS Verticillium dahliae (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=27337 {ECO:0000313|EMBL:RXG43161.1, ECO:0000313|Proteomes:UP000288725};
RN [1] {ECO:0000313|EMBL:PNH35086.1, ECO:0000313|Proteomes:UP000236305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12008 {ECO:0000313|EMBL:PNH35086.1,
RC ECO:0000313|Proteomes:UP000236305};
RA Fan R., Armitage A.D., Cascant-Lopez E., Sobczyk M., Cockerton H.M.,
RA Harrison R.J.;
RT "Comparative genomics yields insights into virulence evolution of
RT Verticillium dahliae.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RXG43161.1, ECO:0000313|Proteomes:UP000288725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Getta Getta {ECO:0000313|EMBL:RXG43161.1,
RC ECO:0000313|Proteomes:UP000288725};
RA Gardiner D.M.;
RT "Genome of Verticillium dahliae isolate Getta Getta.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ketopantoate reductase family.
CC {ECO:0000256|ARBA:ARBA00007870}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXG43161.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MPSH01000004; PNH35086.1; -; Genomic_DNA.
DR EMBL; RSDZ01000114; RXG43161.1; -; Genomic_DNA.
DR OMA; RKEPFQV; -.
DR OrthoDB; 1354873at2759; -.
DR Proteomes; UP000236305; Unassembled WGS sequence.
DR Proteomes; UP000288725; Chromosome 4.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR PANTHER; PTHR43765; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR PANTHER; PTHR43765:SF2; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000288725}.
FT DOMAIN 57..228
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 264..411
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 432 AA; 47520 MW; BDB3B10CFA2A48BC CRC64;
MASPNPPWLQ SVFDDCTAAP KLFAWTPANI SSRTQALSQT RASGSQVPTA SEKTRRIFVL
GVGNLGVLFA TSLAKLAPRP PITLVVHRKE LLEQWASDPS LKISRNGVSE RMTGFDIEWW
TDQKPDHGVV KHVADGGAIP NLVVTTKASA ALPEVDRLRR YLDEDSVVAF AQNGMCKLWP
PHGRAYTSHR YASRPPPSWL ACVTTHGVTS RGRYTSEHAS VADLKIGSVL SGPRGGPSST
YLAEQLARAP FLHGQQVMRA ELWTLQLEKL VVNCIINPLT ALLRCKNGYL FEKPEGPLMR
LIDVLLAEAS AVLQQVIQHP SSDAILDDAQ NTTSVNDRQM LLERFSQTQL KQMLLVVGHK
VRDNTSSMLQ DVRAGRQTEI QDFNGWLVDM AAFLDPGLDT SNHELLIELV ENGVDVDETS
IESHFPVLSG QV
//
