ID A0A2J8DF84_VERDA Unreviewed; 446 AA.
AC A0A2J8DF84;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Mannose-1-phosphate guanyltransferase {ECO:0000256|ARBA:ARBA00018601};
DE AltName: Full=GDP-mannose pyrophosphorylase {ECO:0000256|ARBA:ARBA00031190};
DE AltName: Full=GTP-mannose-1-phosphate guanylyltransferase {ECO:0000256|ARBA:ARBA00030179};
GN ORFNames=BJF96_g8063 {ECO:0000313|EMBL:PNH28684.1}, VDGE_05367
GN {ECO:0000313|EMBL:RXG44601.1};
OS Verticillium dahliae (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=27337 {ECO:0000313|EMBL:PNH28684.1, ECO:0000313|Proteomes:UP000236305};
RN [1] {ECO:0000313|EMBL:PNH28684.1, ECO:0000313|Proteomes:UP000236305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12008 {ECO:0000313|EMBL:PNH28684.1,
RC ECO:0000313|Proteomes:UP000236305};
RA Fan R., Armitage A.D., Cascant-Lopez E., Sobczyk M., Cockerton H.M.,
RA Harrison R.J.;
RT "Comparative genomics yields insights into virulence evolution of
RT Verticillium dahliae.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RXG44601.1, ECO:0000313|Proteomes:UP000288725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Getta Getta {ECO:0000313|EMBL:RXG44601.1,
RC ECO:0000313|Proteomes:UP000288725};
RA Gardiner D.M.;
RT "Genome of Verticillium dahliae isolate Getta Getta.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in cell wall synthesis where it is required for
CC glycosylation. Involved in cell cycle progression through cell-size
CC checkpoint. {ECO:0000256|ARBA:ARBA00024813}.
CC -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC {ECO:0000256|ARBA:ARBA00007274}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNH28684.1}.
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DR EMBL; MPSH01000032; PNH28684.1; -; Genomic_DNA.
DR EMBL; RSDZ01000080; RXG44601.1; -; Genomic_DNA.
DR OMA; MPVPNWW; -.
DR OrthoDB; 5486038at2759; -.
DR Proteomes; UP000236305; Unassembled WGS sequence.
DR Proteomes; UP000288725; Chromosome 2.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IEA:UniProtKB-EC.
DR GO; GO:0044271; P:cellular nitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd06428; M1P_guanylylT_A_like_N; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR018357; Hexapep_transf_CS.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR PANTHER; PTHR22572:SF104; MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE ALPHA; 1.
DR PANTHER; PTHR22572; SUGAR-1-PHOSPHATE GUANYL TRANSFERASE; 1.
DR Pfam; PF00132; Hexapep; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000288725};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 18..218
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 446 AA; 49198 MW; 35DA5E08716CD706 CRC64;
MSLQIPTRGK TQDAATTKAV ILVGGPSRGT RFRPLSLDVP KPLFEVAGHP IIWHCLAAIG
RIPDGQISEV LIIGYYDETV FRDFIKDSSK EFPGLSIKYL REYEALGTAG GLYHFRDAIL
KGRPDRLFVL NADVCCSFPL VEMLALFDDK DAEAVILGTR VSDDAATNFG CIVSDAHTRR
VLHYVEKPET RVSNLINCGV YLFATDAIFP SIKTAIKRRA DRPSRLVSYP SSENLENSYV
FHNDEDDDEE RKNEVIRLEQ DILSDMADTK HFFVYETKDF WRQIKTAGSA VPANALYLQK
AQQQGSPELA KPSANILPPV FIHPTATVDP TAKLGPNVSI GPRAVIGPGV RIKEAVVLED
SEVKHDACVL YSIIGWGSRV GAWARVEGTP MAVNSHTTSI IKNGVKVQSI TILGKDCGVG
DEVRVQNCVC LPYKELKRDV ANEVIM
//
