ID A0A2J8K7I1_PANTR Unreviewed; 397 AA.
AC A0A2J8K7I1; A0A2I3RPJ2;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=UNC93-like protein MFSD11 {ECO:0000256|ARBA:ARBA00040302};
DE AltName: Full=Major facilitator superfamily domain-containing protein 11 {ECO:0000256|ARBA:ARBA00041910};
GN Name=MFSD11 {ECO:0000313|Ensembl:ENSPTRP00000066570.1,
GN ECO:0000313|VGNC:VGNC:9377};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000066570.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000066570.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000066570.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the unc-93 family.
CC {ECO:0000256|ARBA:ARBA00009172}.
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DR EMBL; AC194806; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2J8K7I1; -.
DR Ensembl; ENSPTRT00000102482.1; ENSPTRP00000066570.1; ENSPTRG00000009693.6.
DR VGNC; VGNC:9377; MFSD11.
DR GeneTree; ENSGT00390000012918; -.
DR Proteomes; UP000002277; Chromosome 17.
DR Bgee; ENSPTRG00000009693; Expressed in heart and 21 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17407; MFS_MFSD11; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR010291; Ion_channel_UNC-93.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23294; ET TRANSLATION PRODUCT-RELATED; 1.
DR PANTHER; PTHR23294:SF0; UNC93-LIKE PROTEIN MFSD11; 1.
DR Pfam; PF05978; UNC-93; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 397 AA; 43322 MW; 75DA3D5BBF3E3B51 CRC64;
MSPESKKLFN IIILGVAFMF MFTAFQTCGN VAQTVIRSLN RTDFHGSGYT SMAIIYGVFS
ASNLITPSVV AIVGPQLSMF ASGLFYSMYI AVFIQPFPWS FYTASVFIGI AAAESDRRTV
FIALTVISLV GTVLFFLIRK PDSENVLGED ESSDDQDMEV NESAQNNLTK AVDAFKKSFK
LCVTKEMLLL SITTAYTGLE LTFFSGVYGT CIGATNKFGA EEKSLIGLSG IFIGIGEILG
GSLFGLLSKN NRFGRNPVVL LGILVHFIAF YLIFLNMPGD APIAPVKGTD SSAYIKSSKE
VAILCSFLLG LGDSCFNTQL LSILGFLYSE DSAPAFAIFK FVQSICAAVA FFYSNYLLLH
WQLLVMVIFG FFGTISFFTV EWEAAAFVAR GSDYRSI
//
