ID A0A2J8L984_PANTR Unreviewed; 148 AA.
AC A0A2J8L984; A0A2I3RWM6;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Receptor activity-modifying protein 3 {ECO:0000256|ARBA:ARBA00041072};
GN Name=RAMP3 {ECO:0000313|Ensembl:ENSPTRP00000068714.1,
GN ECO:0000313|VGNC:VGNC:14081};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000068714.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000068714.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000068714.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- SIMILARITY: Belongs to the RAMP family.
CC {ECO:0000256|ARBA:ARBA00007087}.
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DR EMBL; AACZ04038135; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_001151180.1; XM_001151180.5.
DR AlphaFoldDB; A0A2J8L984; -.
DR Ensembl; ENSPTRT00000105927.1; ENSPTRP00000068714.1; ENSPTRG00000019160.6.
DR GeneID; 739151; -.
DR KEGG; ptr:739151; -.
DR CTD; 10268; -.
DR VGNC; VGNC:14081; RAMP3.
DR GeneTree; ENSGT00940000161026; -.
DR OMA; VAVWKWC; -.
DR OrthoDB; 5359286at2759; -.
DR Proteomes; UP000002277; Chromosome 7.
DR Bgee; ENSPTRG00000019160; Expressed in cortex of kidney and 18 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015026; F:coreceptor activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.10.150.510; Receptor activity modifying family; 1.
DR InterPro; IPR006985; RAMP.
DR InterPro; IPR038126; RAMP_sf.
DR PANTHER; PTHR14076; RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP; 1.
DR PANTHER; PTHR14076:SF2; RECEPTOR ACTIVITY-MODIFYING PROTEIN 3; 1.
DR Pfam; PF04901; RAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..148
FT /note="Receptor activity-modifying protein 3"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015082505"
FT TRANSMEM 118..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 148 AA; 16501 MW; 345C24B4EDA4C7C2 CRC64;
METGALRRPQ LLLLLLLLCG GCPRAGGCNE TGMLERLPLC GKAFADKMGK VDVWKRCNLS
EFIVYYESFT NCTEMEANVV GCYWPNPLAQ GFITGIHRQF FSNCTVDRVH LEDPPDEVLI
PLIVIPVVLT VAMAGLVVWR SKRTDTLL
//
