ID A0A2J8MZC1_PANTR Unreviewed; 858 AA.
AC A0A2J8MZC1; A0A2I3T102;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Acetyl-CoA carboxylase beta {ECO:0000313|Ensembl:ENSPTRP00000082924.1};
GN Name=ACACB {ECO:0000313|Ensembl:ENSPTRP00000082924.1,
GN ECO:0000313|VGNC:VGNC:4913};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000082924.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000082924.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000082924.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04070363; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC193909; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2J8MZC1; -.
DR Ensembl; ENSPTRT00000093098.1; ENSPTRP00000082924.1; ENSPTRG00000005420.6.
DR VGNC; VGNC:4913; ACACB.
DR GeneTree; ENSGT00940000155049; -.
DR Proteomes; UP000002277; Chromosome 12.
DR Bgee; ENSPTRG00000005420; Expressed in hindlimb stylopod muscle and 21 other cell types or tissues.
DR GO; GO:0003989; F:acetyl-CoA carboxylase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR Gene3D; 2.40.460.10; Biotin dependent carboxylase carboxyltransferase; 1.
DR InterPro; IPR049076; ACCA.
DR InterPro; IPR034733; AcCoA_carboxyl_beta.
DR InterPro; IPR013537; AcCoA_COase_cen.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR InterPro; IPR011762; COA_CT_N.
DR PANTHER; PTHR45728:SF1; ACETYL-COA CARBOXYLASE 2; 1.
DR PANTHER; PTHR45728; ACETYL-COA CARBOXYLASE, ISOFORM A; 1.
DR Pfam; PF08326; ACC_central; 1.
DR Pfam; PF01039; Carboxyl_trans; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
DR PROSITE; PS50989; COA_CT_CTER; 1.
DR PROSITE; PS50980; COA_CT_NTER; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 361..691
FT /note="CoA carboxyltransferase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50980"
FT DOMAIN 695..858
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
SQ SEQUENCE 858 AA; 97469 MW; DC0D027C5B189EED CRC64;
MTVPISITNP DLLRHSTELF MDSGFSPLCQ RMGAMVAFRR FEDFTRNFDE VISCFANVPK
DTPLFSEART SLYSEDDCKS LREEPIHILN VSIQCADHLE DEALVPILRT FVQSKKNILV
DYGLRRITFL IAQEKEFPKF FTFRARDEFA EDRIYRHLEP ALAFQLELNR MRNFDLTAVP
CANHKMHLYL GAAKVKEGVE VTDHRFFIRA IIRHSDLITK EASFEYLQNE GERLLLEAMD
ELEVAFNNTS VRTDCNHIFL NFVPTVIMDP FKIEESVRYM VMRYGSRLWK LRVLQAEVKI
NIRQTTTGSA VPIRLFITNE SGYYLDISLY KEVTDSRSGN IMFHSFGNKQ GPQHGMLINT
PYVTKDLLQA KRFQAQTLGT TYIYDFPEMF RQALFKLWGS PDKYPKDILT YTELVLDSQG
QLVEMNRLPG GNEVGMVAFK MRFKTQEYPE GRDVIVIGND ITFRIGSFGP GEDLLYLRAS
EMARAEGIPK IYVAANSGAR IGMAEEIKHM FHVAWVDPED PHKGFKYLYL TPQDYTRISS
LNSVHCKHIE EGGESRYMIM DIIGKDDGLG VENLRGSGMI AGESSLAYEE IVTISLVTCR
AIGIGAYLVR LGQRVIQVEN SHIILTGASA LNKVLGREVY TSNNQLGGVQ IMHYNGVSHI
TVPDDFEGVY TILEWLSYMP KDNHSPVPII TPTDPIDREI EFLPSRAPYD PRWMLAGRPH
PTLKGTWQSG FFDHGSFKEI MAPWAQTVVT GRARLGGIPV GVIAVETRTV EVAVPADPAN
LDSEAKIIQQ AGQVWFPDSA YKTAQAIKDF NREKLPLMIF ANWRGFSGGM KGRLGTWRDV
SWWKIRAMLP MHIGEGSV
//
