ID A0A2J8PVM4_PANTR Unreviewed; 2476 AA.
AC A0A2J8PVM4; H2QTB9;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=DOP1 leucine zipper like protein A {ECO:0000313|Ensembl:ENSPTRP00000031407.6};
GN Name=DOP1A {ECO:0000313|Ensembl:ENSPTRP00000031407.6,
GN ECO:0000313|VGNC:VGNC:2769};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000031407.6, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000031407.6, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000031407.6}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the dopey family.
CC {ECO:0000256|ARBA:ARBA00008395}.
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DR EMBL; AACZ04027276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_009449876.2; XM_009451601.2.
DR STRING; 9598.ENSPTRP00000031407; -.
DR PaxDb; 9598-ENSPTRP00000031407; -.
DR Ensembl; ENSPTRT00000033987.6; ENSPTRP00000031407.6; ENSPTRG00000018378.6.
DR GeneID; 740570; -.
DR KEGG; ptr:740570; -.
DR CTD; 23033; -.
DR VGNC; VGNC:2769; DOP1A.
DR GeneTree; ENSGT00390000016421; -.
DR InParanoid; A0A2J8PVM4; -.
DR OrthoDB; 23089at2759; -.
DR TreeFam; TF316855; -.
DR Proteomes; UP000002277; Chromosome 6.
DR Bgee; ENSPTRG00000018378; Expressed in pituitary gland and 20 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR GO; GO:0006895; P:Golgi to endosome transport; IEA:InterPro.
DR InterPro; IPR040314; DOP1.
DR InterPro; IPR007249; Dopey_N.
DR PANTHER; PTHR14042; DOPEY-RELATED; 1.
DR PANTHER; PTHR14042:SF22; PROTEIN DOPEY-1; 1.
DR Pfam; PF04118; Dopey_N; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 11..296
FT /note="Dopey N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04118"
FT REGION 558..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1272..1306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..577
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 701..724
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1291..1306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2476 AA; 278683 MW; 41E80E5093E8B80A CRC64;
MNTEELELLS DSKYRNYVAA IDKALKNFEY SSEWADLISA LGKLNKVLQN NAKYQVVPKK
LTIGKRLAQC LHPALPGGVH RKALETYEII FKIIGPKRLA KDLFLYSSGL FPLLANAAMS
VKPTLLSLYE IYYLPLGKTL KPGLQGLLTG ILPGLEEGSE YYERTNMLLE KVAAAVDQSA
FYSALWGSLL TSPAVRLPGI TYVLAHLNRK LSMEDQLYII GSDIELMVEA VSTSVQDSSV
LVQRSTLDLI LFCFPFHMSQ ATRPDMIRIL SAALHVVLRR DMSLNRRLYA WLLGPRSTRH
SNPEEHATYY FTTFSKELLV QAMVGILQVN GFGEENTLMQ DLKPFRILIS LLDKPELGPV
ILEDVLIEVF RTLYSQCKAE LDLQTEPPFS KDHAQLSSKL RENKKTAELI KTANLLFNSF
EPYYMWDYVA RWFEECCRRT LHVRLQIGPG DSNDSSELQL TNFCLLVDFL LDIVSLPTRS
MRVLCQETYI EIQTEHLPQL LLRMISALTS HLQTLHLSEL TDSLRLCSKI LSKVQPPLLS
ASTGSVLQFP SGQNNSVKEW EDKKVSSVSH ENPTEVFEDG ENPPSSRSSE SGFTEFIQYQ
ADRTDDIDRE LSEGQGAAAI PIGSTSSETE TASTVGSEET IIQTPSVVTQ GTATRSGKTA
QKTAMQCCLE YVQQFLTRLI NLYIIQNNSF SQSLATEHQG DLGREQGETS KWDRNSQGDV
KEKNISKQKT SKEYLSAFLA ACQLFLECSS FPVYIAEGNH TSELRSEKLE TDCEHVQPPQ
WLQTLMNACS QASDFSVQSV AISLVMDLVG LTQSVAMVTG ENINSVEPAQ PLSPNQGRVA
VVIRPPLTQG NLRYIAEKTE FFKHVALTLW DQLGDGTPQH HQKSVELFYQ LHNLVPSSSI
CEDVISQQLT HKDKKIRMEA HAKFAVLWHL TRDLHINKSS SFVRSFDRSL FIMLDSLNSL
DGSTSSVGQA WLNQVLQRHD IARVLEPLLL LLLHPKTQRV SVQRVQAERY WNKSPCYPGE
ESDKHFMQNF ACSNVSQVQL ITSKGNGEKP LTMDEIENFS LTVNPLSDRL SLLSTSSETI
PMVVSDFDLP DQQIEILQSS DSGCSQSSAG DNLSYEVDPE SVNAQEDSQM PKESSPDDDV
QQVVFDLICK VVSGLEVESA SVTSQLEIEA MPPKCSDIDP DEETIKIEDD SIQQSQNPLL
SNESSQFLSV SAEGGHECVA NGISRNSSSP CISGTTHTLH DSSVASIETK SRQRSHSSIQ
FSFKEKLSEK VSEKETIVKE SGKQPGAKPK VKLARKKDDD KKKSSNEKLK QTSVFFSDGL
DLENWYSCGE GDISEIESDM GSPGSRKSPS FNIHPLYQHV LLYLQLYDSS RTLYAFSAIK
AILKTNPIAF VNAISTTSVN NAYTPQLSLL QNLLARHRIS VMGKDFYSHI PVDSNHNFRS
SMYIEILISL CLYYMRSHYP THVKVTAQDL IGNRNMQMMS IEILTLLFTE LAKVIESSAK
GFPSFISDML SKCKVQKVIL HCLLSSIFSA QKWHSEKMAG KNLVAVEEGF SEDSLINFSE
DEFDNGSTLQ SQLLKVLQRL IVLEHRVMTI PEENETGFDF VVSDLEHISP HQPMTSLQYL
HAQPITCQGM FLCAVIRALH QHCACKMHPQ WIGLITSTLP YMGKVLQRVV VSVTLQLCRN
LDNLIQQYKY ETGLSDSRPL WMASIIPPDM ILTLLEGITA IIHYCLLDPT TQYHQLLVSV
DQKHLFEARS GILSILHMIM SSVTLLWSIL HQADSSEKMT IAASASVTTI NLGATKNLRQ
QILELLGPIS MNHGVHFMAA IAFVWNERRQ NKTTTRTKVI PAASEEQLLL VELVRSISVM
RAETVIQTVK EVLKQPPAIA KDKKHLSLEV CMLQFFYAYI QRIPVPNLVD SWASLLILLK
DSIQLSLPAP GQFLILGVLN EFIMKNPSLE NKKDQRDLQD VTHKIVDAIG AIAGSSLEQT
TWLRRNLEVK PSPKIMVDGS NLESDVEDML SPAMETANIT PSVYSVHALT LLSEVLAHLL
DMVFYSDEKE RVIPLLVNIM HYVVPYLRNH SAHNAPSYRA CVQLLSSLSG YQYTRRAWKK
EAFDLFMDPS FFQMDASCVN HWRAIMDNLM THDKTTFRDL MTRVAVAQSS SLNLFANRDV
ELEQRAMLLK RLAFAIFSSE IDQYQKYLPD IQERLVESLR LPQVPTLHSQ VFLFFRVLLL
RMSPQHLTSL WPTMITELVQ VFLLMEQELT ADEDISRTSG PSVAGLETTY TGGNGFSTSY
NSQRWLNLYL SACKFLDLAL ALPSENLPQF QMYRWAFIPE ASDDSGLEVR RQGIHQREFK
PYVVRLAKLL RKRAKDKEED FKTVILEGLE MAKHQKNPEE DNSGRTLGWE PGHLLLTICT
VRSMEQLLPF FNVLSQVFNS KVTSRCGGHS GSPILYSNAF PNKDMKLENH KPCSSKARQK
IEEMVEKDFL EGMIKT
//
