ID A0A2J8X737_PONAB Unreviewed; 299 AA.
AC A0A2J8X737; H2PHA4;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Cyclin-G1 {ECO:0000256|ARBA:ARBA00019866};
GN Name=CCNG1 {ECO:0000313|Ensembl:ENSPPYP00000017925.3};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000017925.3, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000017925.3, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPPYP00000017925.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May play a role in growth regulation. Is associated with G2/M
CC phase arrest in response to DNA damage. May be an intermediate by which
CC p53 mediates its role as an inhibitor of cellular proliferation.
CC {ECO:0000256|ARBA:ARBA00025528}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin G subfamily.
CC {ECO:0000256|ARBA:ARBA00010389}.
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DR AlphaFoldDB; A0A2J8X737; -.
DR Ensembl; ENSPPYT00000018643.3; ENSPPYP00000017925.3; ENSPPYG00000016016.3.
DR GeneTree; ENSGT00940000154726; -.
DR InParanoid; A0A2J8X737; -.
DR OMA; CFYIAIK; -.
DR OrthoDB; 3032827at2759; -.
DR TreeFam; TF101007; -.
DR Proteomes; UP000001595; Chromosome 5.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd20583; CYCLIN_CCNG1; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177:SF59; CYCLIN-G1; 1.
DR PANTHER; PTHR10177; CYCLINS; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 1.
DR SUPFAM; SSF47954; Cyclin-like; 1.
PE 3: Inferred from homology;
KW Cyclin {ECO:0000256|RuleBase:RU000383};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT DOMAIN 57..147
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
SQ SEQUENCE 299 AA; 34521 MW; FC61E3FF47D6C9F3 CRC64;
MIEVLTTTDS QKLLHQLNAL LEQESRCQPK VCGLRLIESA HDNGLRMTAR LRDFEVKDLL
SLTQFFGFDT ETFSLAVNLL DRFLSKMKVC LKVQPKHLGC VGLSCFYLAV KSIEEERNVP
LATDLIRISQ YRFTVSDLMR MEKIVLEKVC WKVKATTAFQ FLQLYYSLLQ ENLPLERRNN
INFERLEAQL KACHCRIIFS KAKPSVLALS IIALEIQAQK CVELTEGIEC LQKLSKINGR
DLTFWQELVS KCLTEYSSNK CSKPNVQKLK WIVSGRTARQ LKHSYYRITH LPTIPEMVP
//
