ID   A0A2K0VUB1_GIBNY        Unreviewed;       874 AA.
AC   A0A2K0VUB1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Heme peroxidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=FNYG_13051 {ECO:0000313|EMBL:PNP73610.1};
OS   Gibberella nygamai (Bean root rot disease fungus) (Fusarium nygamai).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium fujikuroi species complex.
OX   NCBI_TaxID=42673 {ECO:0000313|EMBL:PNP73610.1, ECO:0000313|Proteomes:UP000236664};
RN   [1] {ECO:0000313|EMBL:PNP73610.1, ECO:0000313|Proteomes:UP000236664}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CS10214 {ECO:0000313|EMBL:PNP73610.1,
RC   ECO:0000313|Proteomes:UP000236664};
RA   Gardiner D.M., Obanor F., Kazan K.;
RT   "Genome of Fusarium nygamai isolate CS10214.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PNP73610.1}.
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DR   EMBL; MTQA01000258; PNP73610.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K0VUB1; -.
DR   STRING; 42673.A0A2K0VUB1; -.
DR   OrthoDB; 3322316at2759; -.
DR   Proteomes; UP000236664; Unassembled WGS sequence.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProt.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   CDD; cd20612; CYP_LDS-like_C; 1.
DR   CDD; cd09817; linoleate_diol_synthase_like; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   InterPro; IPR019791; Haem_peroxidase_animal.
DR   InterPro; IPR010255; Haem_peroxidase_sf.
DR   InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR   InterPro; IPR034812; Ppo-like_N.
DR   PANTHER; PTHR11903:SF37; LINOLEATE 8R-LIPOXYGENASE-RELATED; 1.
DR   PANTHER; PTHR11903; PROSTAGLANDIN G/H SYNTHASE; 1.
DR   Pfam; PF03098; An_peroxidase; 2.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR   PROSITE; PS50292; PEROXIDASE_3; 1.
PE   4: Predicted;
KW   Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW   Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00022964};
KW   Reference proteome {ECO:0000313|Proteomes:UP000236664}.
FT   BINDING         155
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
SQ   SEQUENCE   874 AA;  97457 MW;  059EDD5FBD6F8E80 CRC64;
     MEEQAKVRTF KDGRLKNDVF SEDRLLTQPP GVCALMIAFN RFHNYVVGEL ATINEDRRFS
     LAKGVTPGHP DYDKAQLKRD NDLFQTGRLV TCGLYVNIIV SDYLRTILNL NRNPIASDWK
     LDPRDDFSEV FDSQGTPRGI GNQVSVEFNM IYRWHSAVSR QDEVWANGFF KEVFGPNANP
     DTMSTDEFLQ GLRKWSWSLP GDPEKWTFGG LTRLEDGRFP DAELVRLLQT GTENVAGKYS
     CNGLGSCRVV KLTNISLLGA FGARNIPRVF KALEVYGIQQ GRQWGLATLN EFRLFFKLKP
     YTTFADMNSD PSVAEALEAM YGHPDNVELY PGLLAEETKK PLEPGSGLCP GFTTSFAIMS
     DAVALVRGDR FYTVDYSPSN LTSFGYTEVS SDFDVAGGGM MYKLLMRAFP GWYRANSVYA
     LYPFTTPEAN FEALMKLGTS QDFDFNKPSF IGPPTPITSW QGVVDVLSDQ EHFHVPWGNH
     TFQLTHHGYM LSGDAPANTE QRGFVKQCLY SPESGLEEVR HFYESITAEL FRQHSRKVGE
     SYQVDIVRDI GNLAHAHFTS QFFGIPLQEY GAGSDSYTAR ALSDVLANLF GYVFLDLDTA
     ASYKNRVVAA AETKSLGEKM QTTVAGIKAQ RFPSLHHMLR TASSDGVLRS YGVELIDRML
     ESGKGVDEAV WTIIPTAAAA CATQAQGWAQ MIDLYLSDKY YSHWHAIQKL AMSDEPEAFE
     KLKKYALEGF RLSTPAFGLL RTVVADKADL RDGPRVVSVK KGDTIFTNFV AAGLDATKFS
     DPYEIKLDRP DDLYIHHGWG PHACLGRPIV TVAGASMLRV CARLGNLRRA PGHAGEMKSK
     TVNDAFKVYL AENGSKWGPF PVSKKVVFDK TTEM
//