ID A0A2K0VZR3_GIBNY Unreviewed; 7815 AA.
AC A0A2K0VZR3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=FNYG_11139 {ECO:0000313|EMBL:PNP75510.1};
OS Gibberella nygamai (Bean root rot disease fungus) (Fusarium nygamai).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=42673 {ECO:0000313|EMBL:PNP75510.1, ECO:0000313|Proteomes:UP000236664};
RN [1] {ECO:0000313|EMBL:PNP75510.1, ECO:0000313|Proteomes:UP000236664}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CS10214 {ECO:0000313|EMBL:PNP75510.1,
RC ECO:0000313|Proteomes:UP000236664};
RA Gardiner D.M., Obanor F., Kazan K.;
RT "Genome of Fusarium nygamai isolate CS10214.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNP75510.1}.
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DR EMBL; MTQA01000168; PNP75510.1; -; Genomic_DNA.
DR STRING; 42673.A0A2K0VZR3; -.
DR OrthoDB; 2787863at2759; -.
DR Proteomes; UP000236664; Unassembled WGS sequence.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR CDD; cd05918; A_NRPS_SidN3_like; 7.
DR CDD; cd19545; FUM14_C_NRPS-like; 7.
DR Gene3D; 3.30.300.30; -; 7.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 7.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 7.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 6.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 8.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 7.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 7.
DR Pfam; PF00668; Condensation; 7.
DR Pfam; PF00550; PP-binding; 7.
DR SMART; SM00823; PKS_PP; 6.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 7.
DR SUPFAM; SSF47336; ACP-like; 7.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 15.
DR PROSITE; PS00455; AMP_BINDING; 6.
DR PROSITE; PS50075; CARRIER; 7.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 2.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000236664}.
FT DOMAIN 798..871
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1883..1960
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2939..3016
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4033..4110
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 5093..5169
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 6187..6262
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 7270..7346
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 7815 AA; 859320 MW; 44453AC5A4E40931 CRC64;
MTLLNGKSTL ANCDNPSIEP PNGKTKPNGY TKHEMPIPSD WQRYLIDIDH AAVSLFESPK
PDDPVATVKS THLFGLAEET LLVSNPSMIC AAFAIVMSEY SNSQDVLFGV RAGGRVVPLR
VLVDKNDQIS SFLDQVESKR KMAQDFPPEM PLPAVHNVLA FVEDKMPTSE HGLVSENDAI
SIEISLDSKE IAIQVLFNPA CADLLTVQRF LKQLETVFHQ LCKPSAGQLI EEVKSITADD
IRDMASWNSD CLTPYTPECI HDVVKQHVLT SPNSCAVHGW DGDLSYAQLD EESSRLANYL
YRQGVRPHDL VPLAFHKSIW FTICALALSK LGAAIVPLDP QWPKDRQMYI INDIESRRII
TNIPNPASVY AGLEIIDISQ LSIANESVTA KYPVTPEHAI YAYYTSGTTG QPKGCVIEHG
AFVSSSLKRV KFMGRNRDSR ILQVTTYTFD VALDDIFFTL MTGGCLCVPT REECLNDIAG
AVEKYNCNTL HVAPSLARNL QPSQVPSLRA LILGGEAMSA SILRTWAGSV ALYNSYGPTE
CCIACCMNLI QSPDENPRKI GRPKDCSYWL VRPGDIDTLA AIGTVGEILI HGPNLGRGYL
NKPELTAKAF PQNISWASEV GLPADARFYR TGDLARFNAD GSICLLGRID DQVKIHGQRI
ELGEIDYRLG QCLPAGIEAI SGVVNFRDRE VATLVAFIQT VNSDSNSANS SGSLALADTD
NWNQFHRLRS HVMEQLSHNL PSYMVPSVFL PVQNFLYFNQ GKLNRRGMFQ QASQFRLDDI
LSTNTSSGQE TQHASSWSAE AIVLRQLWAL ALGLDEKNIH LDSSFADLGG DSLAAIRLGT
LCRPYDIQLS VDDIRQQSTI LLQAEMSEKK KKSEERRVAP AAILPAGKRF GLLGQDVDVG
ILCEQASAQC QIDSGAIDDI YPASPLQESL MALSMDDSPY VSQFVFRIPD NLDMYRFRKA
WKSAFSDIPI LRTRIICLQD LGTLQVVVDE DIEWTEHKNI TLLQFLKDNQ ERLMQVGDRL
VRFAVVQETP GTSFLVWTCH HACHDGRTVD QTLRIVGAKY LDRPVSSPVP YYRYIQFQQD
LYRRDWQEYW KLSLAGASVS AFPAQDNAMH RPVTDASHQY SFSMPRISTD KSNTSVFSSS
SILRAAWALI VSRYEESEDV TFGTIVGANA SAVADVDAIV GPTNNTIPVR VLASEGWTVE
AFVSHVKQQF DYSPFQHIGL ANLKDLSPEM QDIVNIRNLF VVQSHFVGQT GSEINLERVP
VSAHEGFKYP LVVECFQENA NQVLVNFIYD SHILDQSQIS RLALQFENTI HLLSNSPQKT
LNEIEILSPS DVAQILEWQA NVPLPSSFCL HQQFFSQVKK SPNAIALCTW EGEYTYLELE
NLVNSLAMYL QDAGLRHGDR VLFQIEKSAC AVISFLATLK LGGTCVILGA TWPRIRSEVI
AADTKANFLL VSPTLSNASV GLVPNILEVS TSFIQGLPRP TYHVDSVYQP SDLAFILFTS
GSTGTPKGVQ LAHSGLVTNF ASMAQHMMYT SETRLFQFSD FTFDLSIYDI FGMLMIGGCI
CMPSEQERHG DLMGSMNRMK VNAATATPSI AKMIKPSSVP TLRRIKLGGE ALDPTTLATL
AGSIDTENGY GVTESSVWST CTHRLSPDSD PKNVGRGINC YTWIVDTKNP NRLRPIGAVG
ELILQGPGVA LGYINKPEES KRVFLDALPW SPDKGRAYRT GDLVKYAPDG SLIYVQRKDA
QLKIRGQRFE ASEVESHLQQ CGLPEGKFCV DLVQTQTGPV VVVFLCINKR IEMKDASDLG
IVPLDQQDSS VVDQMAQAMR MLIPRLPSYM IPQAVIPVTQ MPVSNSGKLD RRALRSLVTG
MSPGKLRQLL RPSEGSVCQK KTNLETEAER TMALLWSQVL PIDESHVFHI DDDFFQLGGH
SITLMRLISA GRSHGMLISY RDAFLHSSLG AMSRQATVRN EVEHVLPRSI QPFAMAPSDV
DRLIQEVSRA CQVDSQDIVD LYPCTPFQES MMTLSLSKPG LYTAQFVWSL PDTIDLERLR
SAWETLVECN AILRTRLIYS STYWQVVTST GIDFTVTDTS IDSYLKNDKA RPIRLGESLN
RLAIIRDQSS TTQYLAWTAH HSTYDGHSWS CIQDWLSDLY TQGGRKLPLV PFNVFVDHIV
SNPLPETGLS FWKDMMSGAR MPSFPKLPLN NDLQSTNSVV TQSVSLPGQT SSDVTVASAI
QAAWAILLGQ YENSDDVLFA ATLSGRNVAV DGIENIAGPT SCTVPLRVRI DQGQDTSSWL
RSVQQSYVDA VTYGQIGMNN ISLVNKDAEV ARHIRSLLIV QAPTSKTVSG LERIGCRKIE
TKAKGFLSYA LVVECTPSME SDEMEVMLLS DNYKTIGDMC LASPSDMETI STWNKELLVT
VDATVHALFD QRLSQKHNAT AISSWDGEMT YVELDNYSSL LAAHLMASGV KPGQYIPLCF
EKTMWIVVSM LAVLKAGGAC VCLDPNHPSR HHQVILSRVS AEIVITSPAN ESKFPDHRVL
SVSAALMTKI AGDPYIAPLV TSDQPAFVVF TSGTTGEPKG IVLEHRALCT SIQAHGQFME
FGPESRVLQF ASYTFDVSIA EILTTLVFGG CICIPSDHAR LNNLSGAIRT LRANQAYLTS
SVAALLDPDT VNGSLKVLSV GGEQVGQDVL TRWGDRTTLL NMYGPAETTI WCGGKHSVKP
GDDAANIGYG VGARMWLTDV NDVQKLAPIG AVGEIVIEGP LLARGYINGD NTVFVESPDW
AKAFDIVDGF DRVTGRVYRS GDLGRYQSDG SIVICGRRDT QLKIRGQRVE VSQIEDQLQR
LAPDFKCVVG VLRTDTPTLV AFIGLERPQD QRLAGTIDLV VSGSDLSAEV RDLISGLESQ
LTNILPPYSV PAHYLVLRKI PLMTSGKTDR KKLQLIASEH LEHSVNESKS QTLQQVKKIP
TTEMEWNLFG LWAQVLGVNN LASLGTDDNF FRCGGDSLKA MQLASLASQR GITLQVSDLF
KHPVLADLAQ ALVLEVPKVI ETSPVQDSPE PYSLLPRDTK EQVKAQAALD CDVSPNLIGD
IYPCTPLQDG LFALSQKQPG AYVAQFKFSV SNRINIRRLR QAWETVCDQA PILRSRLVST
PSGIVQVVLT EDFWWYEQHD IDTSAELEKD KAAIGGLGQP LQRFRLIQDV VTGQKNLVWT
LHHAAYDGWS IQRILERVRL VYQDQPIPSP CVPFNAFIRY SSGIAENHES KEFWQSYLSN
ITPPTFPALP SPTYQALADT VIESKLSNLE LPHSFTLTTV LRAAWAIVVG TYQRSDDVVF
LTTVFGRNAP LAGIDTIIGP TITTIPIRVK LDDPNTTVDT LLEAIQESAT ETMAFEQLGL
QSIRNTSTDC KAACMAQNLL VIQTSHGDDA NVAFDGFEKL PDEAKGFSTI PFTLECTATS
EGGLSIEASF DSKVVDPAQA NRIIKTFEHV TNQMCRTHLK LSQVDLISHP DHDLINNWNS
TMPCAKEQCI HHQLDLLAAS NPDAESVCAW DGNFTFKELN FLSNRYAAYL QSQGIQPGNF
VPFCFDKSKW VVVAMLAIMK VGAASVTIDP KHPPGRRDGI LSAVSASAVV TTSVHTHLFD
NNASHGLKTL VLDEETMNNI PDSLQPAEIE STPNDAAFVV YTSGSTGTPK AVVIEHRGIC
TGAFHLANLL HLGPQTRCLQ FAAFTFDQSF GDIFHTLLLG GCVCIPSESD RLNDLVGSIL
RLKANTAILT PTVACSIDPN ELGSHKMDVL TVGGEPVTAE AIRTWAPHVR LFNTYGPAEC
SVTTIGRPID MRNITQPANI GRGLGALVWL TYPDDPERLT PIGTVGEILM EGPQLARGYL
NDSKNTNAAY ITDPAWSHRF PVPGMSAPRR FYRTGDLGQY QPDGTIVCLG RRDSQVKLRG
QRMELGEVEH HISTYTQSAV EIITDVFTPP NGTATLVACI SLKGHETKGD ECQVEVDEQV
LTRFSAMLSG LDSYLSRMLP AYMIPTLYMP VTHIPLTPSG KKDRKSIRLM LACVTVNQLQ
KMRTILGESE PSRPLTEREK DLQQLWAKVL KLDGETIINA NANFFHSGGD SVRAMALVAA
ARREDTHLTV ADIFSHPKLC DMAAITTSLS QKDQPVELAS YSLLPSKPSA YTLSEACGAC
DVDQAQIQDM YPATPLQQAL VALSIKDSGA YVSNFVFLLP SHLGTELFQR AWEHVYASSH
SLSTRVVDTV TAGMLQVVVS EKVRWSHGDN LEAFVGRQSQ KGFKLGQSMA ESGIVRQKDG
KTFFVLTLHH AIYDGWSLRR LLEATEQIYH GQTIPRFVTF NRFVAHVSRS EDNRTPVFWR
SYLEGVPMAS FIQQATTAYK PTADHIISQD VSLSDNFTAR SGVTVTSLIR AAWALVLATY
NSDKTSDVVF GIVVGGRSLD LADIEYIDGP TIATVPFRVT FDPTAPVDML LQGVQNKSTQ
ILQHEQFGMQ NIIKVSDDAR LACDFETLLV IQDSAEIKAS SGFLDMDNLY QRPDKPPSIP
LVVECSPSAS NLHLDIHFDA KLLEETQATR LIRQLAHVIK QLANSVPSLS LSCIDMINPA
DAEEIKDWNR KPPPTFNGCL HEMVLQNSKD CPDRIAIQSW DTSLTYSELD HLSGILAQYL
NNVGVRPEVK VPFCMDKSAF AIVAMLAILR CGGCFVPLDM SSPIKRLKNI IRRVNAKFIL
VSPKTRPLFE DLEGQLVEVT RSMIDGLPKL SKSLYNPSPT HPAYVLFTSG STGTPKGVVV
EHGAIATSVS SFSSYLGFTP DVRVLQFAPY VFDVSIGEIF ACLVSGGCLC IATEPSLMDD
LPLCIQQLNV NFAVLTPTFA QTVTPSEVPS LQTLVLGGEP LRKKDVETWA TAVKLFNGYG
PTEASVLAMA HCCRSWIVSP SDPNILLPIG AVGELVLEGN TLARGYLDTE SAQEAFITDP
KFLDHLVPEA TGSRVYKTGD LVRYNADGVV EFVSRKDTQV KFHGRRIELE DIEHNAMEAM
PEAKHLVVEL VRPGNSQHEA LALFFHTKSQ RTANEEQPIL PIEADLRARL RDIKSNLSVT
LPSYMVPSLY IPLSKWPSTS NGKLNRHLLR SLVSDFTSEA VATYSLHTGD SSALSSDEEK
QLAQLWATTL NIDARTIGSS DSFFQHGGDS IAAVRLVTLA REQGIGLSVD TLLSKPILRD
MALCMTSAQP VEETIVKPFC QIYSRQEEIL LAASQFGVEP AMIEDIYPCS ALQNSLMAVS
LKNASAYLSQ FVIAIPEGLD IEVLQAAWNT VYSDSPILRT RFYQPSLNNM QHPMLQTVVD
EEPKWGTEEN LDEFLRRDKQ TPTCLGSPLT RFTIVVDKAT HERFFVLTAH HAVYDGWSIA
STFEKVEMTL KGVALPKSVG YNVFIHHVQS LNTQEKKAFW SSTLEGTTQT LFPQLPSHSY
EPATDDCLEH QFAYPADLAP HSTVTMATVV RGAWGLLVSK YCDSSDVVFG TTVNGRMAPI
PGIEKVQGPT IATIPFRARS STHQSILSYL EQLHVQQIES IPHEQYGLQN IKHLSEPIAR
ACEFQNLLVI QSSHESSFSD SSSAFGTVKN MDQGSLSMRG FHNMALVVEC SIDSEAIHVT
VNFDSNVIPK AQVQRIARHL EHLILQLQAG STQSDLKMDQ IDHVSPSDQA EILEWNSSIP
GSVRSCVHEL FESRARLQPS APAICARDGQ LTYFELEVKA TTLAAYLSLQ GLARGVLVPL
LFEKSCWAVV AMMAVLKAGA ANVTLNPEHP QARLEDSINA TQGEVILCSR KYFELASSFD
AQVIVVDEDL FHHIDLPSLT SFDSWSPTRI AGPDDPCFVL FTSGTTGKPK GIVINHAAMC
SSINGHSATL RYSTGPGSRN FQFTAYTSDV SIGEIFTSLA MGSCVCVPSD YDRMNNLAGS
MRDLNVNWAF LTPSVAALLK PEEVPSLRTL LFGGETATPE NISTWADSVY LINSAGPAEC
CIWTHCNPGI STADIGSNWG YNLGCATWIT DPNNPSVLMP IGVTGEMLIE GPNLAQGYLN
DPERTQKAFV EIHLAGKKRR LYRTGDLARL MADGKTQFLG RRDTQVKLRG QRVEIGEIEN
QIRRHIPDST LVAVEMVRIA GGKSAPLLAA FHAPKDPQVT DKNGDIPQAE VLSAAKVQEL
GVILDELAAK LAEALPQHMI PTAFIPLTSM PLTASAKTDR NVLSALASTI SVEQLSYYAL
SSAEKQFPSS RAEQQMAKLW QEVLNTEIDI GIHDSFFRIG GDSISAMDLV SRSRAVGISL
TVEQIFKNPT LQHMAAIATT FTESMGSITV EPFSLIPQTG TLDIVCSEAQ EQCQVTAQQI
QDIYPCSALQ EGLLALSLKT SGSYLAQMVF EIPDELDLER FKDAWAHMVA KAAPILRTRF
FESPSQGHQL MQAVIDAPLE WTYGDNLDKY LMTDSTKIVQ LGQPTSRYAI ISNTQRFFVF
TAHHAVYDGA SLGPMFEAVG KVYSENLVNS SSPYSIFVQY LLGMDSDSSK AYWEMSLQGA
PAPTFPRLPS IDYRPMTNDA LKRTIALPAR HATEFTMSSI VRAAWSLVVA SYSDTDDIVF
ASTVGGRTLP IAGIENIIGP TLATVPVRVT IDRNASVSDF LTMIQEQSTS MMPHEQYGLQ
NIKRISSSIS AASELHNLLV INTSSVEGLG SGVLGLKQVD LGRADGFHNF ALSIECTAEA
DALSLAVSFD NHVIDPRQIR RVVDQLEHML QQISTCSIHT RLADMHLTGP ADMGEIQLWN
SHVPPPQQTY VHTLVEQRVK SQPDSPAVCS VEGELTYREL DELSSSLANH LISTFAVAPG
TLIPILFEKS IWTVVTMLAV LKAGGANVPM DPEQPLPRLQ ELAADIGATL AISSSKYQDK
AQNVTARSMF VDREVLTAID KTPICPTSTV SYEDPAFILF TSGSTGKPKA ILIDHTAFTS
SIKGHGEILR YRKGSRNLQF TAYISDVSIG EIFTSLSAGA CVCVPSDFER MNDLAGAINR
MRVDWAFLTP SVASLLDATK VPSLKTLVFG GETATPENIA VWAPRLFLIN SFGPAECSIW
THCDPGVGIT HNGSHIGYAI GCATWIVDPN DYNKLVPIGS IGELIVEGPN VARGYLDEAK
TKEAFLETAS WMPNGRKNRL YKMGDLVRYL PDGKIQFLGR KDSQVKLHGQ RIELGEIEHQ
LRVALAKHDA DRNVQVAVEM VSLSTDSSTS SLLTAFVDYE GISPDDGPAR LSSGEKAQQW
ARQMFRATHD HLALTLPRHM IPSMLLPLTR MPLNGSAKTD RKVLKQIVSG MDTIQRALYS
LATGETSIIK AATPNEKTLH HIWSDILSIS PETFGVEANF MSLGGDSIAA MKMIPIAQAA
GLSISVEDLF THPVLRDLAR VSHQGTTEQS QDIPPFSLVE QAPNQDKLLA EASIHCNLPP
DAIQDIYPCT QVQEQFISTT QIQPGAYTLQ DVFKLSSDMD LARFKIAWTR TVASHVALRT
RIFLSNDRHQ HLQVVQNASE SLDWIYSENL EEYLKADKAK SMRYGESLVR SAIVSEGVEK
HFVVTYHHSI YDAVSLGIIM NGLEAFYLDD PYEVKEPKYN AFVHHLTRAK SQELSSQFWR
EHLAGNGSSI TPLYQPVDGA RVDSLLRHTI TFPMHYQQSQ LSMTVAAFTY AALSLVTARL
TGSSSAVLEL TLLGRSVPVK GIERMVGTTV TSAPLRIDIT AGNDKPWTAT LKDYLDYAKQ
RSSSIVLHEH TCMPDPETKH ITSAALPIVV HPSNPHKEAL GTGIGLQRRE IQSMGQSASA
FYMDIAALDG EGLEINLPFD SRIVDRGAVI RLVSLFEMAV VQIMRLSAGG GLDAFLDDLD
WDFPNLSIAI EEYAG
//
