ID A0A2K1E789_9SPHN Unreviewed; 589 AA.
AC A0A2K1E789;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=recQ {ECO:0000313|EMBL:PNQ76136.1};
GN ORFNames=BA950_10040 {ECO:0000313|EMBL:PNQ76136.1};
OS Erythrobacter sp. SAORIC-644.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Erythrobacter/Porphyrobacter group; Erythrobacter.
OX NCBI_TaxID=1869314 {ECO:0000313|EMBL:PNQ76136.1, ECO:0000313|Proteomes:UP000236145};
RN [1] {ECO:0000313|EMBL:PNQ76136.1, ECO:0000313|Proteomes:UP000236145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAORIC-644 {ECO:0000313|EMBL:PNQ76136.1,
RC ECO:0000313|Proteomes:UP000236145};
RA Song J., Kogure K.;
RT "Erythrobacter sp. SAORIC-644 genome sequencing.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNQ76136.1}.
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DR EMBL; POYF01000005; PNQ76136.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1E789; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000236145; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:PNQ76136.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 28..194
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 215..363
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 516..589
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 589 AA; 64158 MW; B74F08D1751D1E2D CRC64;
MSGIAGAYQS LKDVFGFDGF RGRQEDVVTR ILAGASTLAV MPTGAGKSLT YQLPAVMLPG
TCVVISPLIA LMHDQLRSAR ANGIRAATLT SADADWRETQ DAFRAGELDL LYVAPERASQ
PAFREFLNSA PLCLFAIDEA HCVSEWGHDF RPDYRMLRGL MDAFPRVPRL ALTATADRQT
RADVMAQLGI AEDGLVLAGF DRPNIRYAIR HRDNPVRQLT TLMESEPGPG IVYAQTRRKV
EDLADKLAAA TGRAVRPYHA GLDARVRAAN QSAFVASEDM VIVATVAFGM GIDKPDVRFV
AHVGVPKSIE GYYQETGRAG RDGDPSQAVM FWGAGDFATA RQRLAEVDET RRAAERTRLD
ALAGLVETAE CRRAVLLRHF GEHPPASCGN CDNCLEQPDV TDATELARKL LSAVYRTGQS
FGMGHLQKVL TGSEDERVRQ RGHDRLSVFG IVEPAEAVML QPLSRALQAR GDLVANEHGG
LALGGSARAI LKGESAVKIV VPPKRRRGRR GDMTPNPVGD PLFEALRALR KELAEDAQVP
PYVIFHDSTL REMAAARPAT LDQLGRLPGI GAKKLEAYGD RFLRAIERH
//
