ID A0A2K1IS25_PHYPA Unreviewed; 599 AA.
AC A0A2K1IS25;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=BHLH domain-containing protein {ECO:0000259|PROSITE:PS50888};
GN ORFNames=PHYPA_026208 {ECO:0000313|EMBL:PNR32083.1};
OS Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR32083.1};
RN [1] {ECO:0000313|EMBL:PNR32083.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c21_15150V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=18079367; DOI=10.1126/science.1150646;
RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA Boore J.L.;
RT "The Physcomitrella genome reveals evolutionary insights into the conquest
RT of land by plants.";
RL Science 319:64-69(2008).
RN [2] {ECO:0000313|EMBL:PNR32083.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c21_15150V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=29237241; DOI=10.1111/tpj.13801;
RA Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA Schmutz J., Rensing S.A.;
RT "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT structure and evolution.";
RL Plant J. 93:515-533(2018).
RN [3] {ECO:0000313|EnsemblPlants:Pp3c21_15150V3.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (DEC-2020) to UniProtKB.
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DR EMBL; ABEU02000021; PNR32083.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1IS25; -.
DR STRING; 3218.A0A2K1IS25; -.
DR EnsemblPlants; Pp3c21_15150V3.1; Pp3c21_15150V3.1; Pp3c21_15150.
DR EnsemblPlants; Pp3c21_15150V3.2; Pp3c21_15150V3.2; Pp3c21_15150.
DR EnsemblPlants; Pp3c21_15150V3.4; Pp3c21_15150V3.4; Pp3c21_15150.
DR EnsemblPlants; Pp3c21_15150V3.5; Pp3c21_15150V3.5; Pp3c21_15150.
DR EnsemblPlants; Pp3c21_15150V3.6; Pp3c21_15150V3.6; Pp3c21_15150.
DR Gramene; Pp3c21_15150V3.1; Pp3c21_15150V3.1; Pp3c21_15150.
DR Gramene; Pp3c21_15150V3.2; Pp3c21_15150V3.2; Pp3c21_15150.
DR Gramene; Pp3c21_15150V3.4; Pp3c21_15150V3.4; Pp3c21_15150.
DR Gramene; Pp3c21_15150V3.5; Pp3c21_15150V3.5; Pp3c21_15150.
DR Gramene; Pp3c21_15150V3.6; Pp3c21_15150V3.6; Pp3c21_15150.
DR InParanoid; A0A2K1IS25; -.
DR OrthoDB; 5970at2759; -.
DR Proteomes; UP000006727; Chromosome 21.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR025610; MYC/MYB_N.
DR PANTHER; PTHR46266; TRANSCRIPTION FACTOR TT8; 1.
DR PANTHER; PTHR46266:SF4; TRANSCRIPTION FACTOR TT8; 1.
DR Pfam; PF14215; bHLH-MYC_N; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006727};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 388..437
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 207..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..228
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 599 AA; 66938 MW; 2CA2FD62FD971B38 CRC64;
MSGSKLEAIK EMTPLVPPEL RLELQAATRA VKWTYSVFWK PASSNQKTLV WGDGYYNGTI
KTRKTIGAKE LTPEEFGLQR SQQLRDLYNS LSDSKTGHQQ ASKPFALKPE DLAEQEWFFL
LCMSCNFAEG VGLVGRAAAD GRYAWQCKTN EISTKLFTRA LLAKSASIQT IFCFPLMDGV
VEFGTTEHVP EDSNIVQHVS SFFMERKRHS HPQHSVTTEQ KHEHSKNSPQ QSENVVHCNQ
LAEYGASSKK AKLSSSQMAE VENETSMNRV NSLLDPTSQE QRTYTHLFQQ NQGSDSRLYK
GENRGKNQSG VLPGRVFSSW KKNSTPSQKS QKAENRQKIL KEALFRVTRL YDGAWKNKVD
SSFIFTDRAV EDRTSNLGSQ KPVPSSEETS ASHVLAERRR REKLNDRFVA LRELIPNVSK
MDKASILGVA IEYVKELQSQ LRALESNNTQ DGTPRQFGTA NEDATITNTT REHLECAGVV
HVIDEDKAAT SECTITEESF KPGHVNVRVS MNNDVAIVKL HCPYRQTLLV DVLQSLNDLE
FDVCGVRSSI SDDILSTVLE AKLRSASDGS SPTIIEVEKT LHRAAAGLLK ERASASSLQ
//
