ID A0A2K1J4W2_PHYPA Unreviewed; 440 AA.
AC A0A2K1J4W2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=DNA repair metallo-beta-lactamase domain-containing protein {ECO:0000259|Pfam:PF07522};
GN ORFNames=PHYPA_022409 {ECO:0000313|EMBL:PNR36558.1};
OS Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR36558.1};
RN [1] {ECO:0000313|EMBL:PNR36558.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c17_21070V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=18079367; DOI=10.1126/science.1150646;
RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA Boore J.L.;
RT "The Physcomitrella genome reveals evolutionary insights into the conquest
RT of land by plants.";
RL Science 319:64-69(2008).
RN [2] {ECO:0000313|EMBL:PNR36558.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c17_21070V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=29237241; DOI=10.1111/tpj.13801;
RA Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA Schmutz J., Rensing S.A.;
RT "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT structure and evolution.";
RL Plant J. 93:515-533(2018).
RN [3] {ECO:0000313|EnsemblPlants:Pp3c17_21070V3.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA repair metallo-beta-lactamase (DRMBL)
CC family. {ECO:0000256|ARBA:ARBA00010304}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABEU02000017; PNR36558.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1J4W2; -.
DR STRING; 3218.A0A2K1J4W2; -.
DR PaxDb; 3218-PP1S68_3V6-1; -.
DR EnsemblPlants; Pp3c17_21070V3.1; Pp3c17_21070V3.1; Pp3c17_21070.
DR EnsemblPlants; Pp3c17_21070V3.2; Pp3c17_21070V3.2; Pp3c17_21070.
DR Gramene; Pp3c17_21070V3.1; Pp3c17_21070V3.1; Pp3c17_21070.
DR Gramene; Pp3c17_21070V3.2; Pp3c17_21070V3.2; Pp3c17_21070.
DR Proteomes; UP000006727; Chromosome 17.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.12650; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR011084; DRMBL.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR PANTHER; PTHR23240:SF31; DNA REPAIR METALLO-BETA-LACTAMASE FAMILY PROTEIN; 1.
DR Pfam; PF07522; DRMBL; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006727}.
FT DOMAIN 222..347
FT /note="DNA repair metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF07522"
SQ SEQUENCE 440 AA; 48807 MW; 300FDAC1E78361B0 CRC64;
MGVESKKYPF SVDTWTEMAM RKPFHFLTHA HKDHTVGIDS HGTHPIYCTS LTEKLVLRRY
PTLHPSLFKN LEIGEPKLLA GEDQAFTVTA FDANHCPGAI MLLFEGSFGT LLHTGDCRLT
IECLNQLPRQ FISGSGRALD CVYLDCTFGN VTMVMPSIEE AIEQVKRCIW NHSSEARVYL
ACDMLGQETL LEAVANSFGQ KIFINKDGLS RYLADLEVVA SDFLTSDSES TRFEICEGFP
KLYKRAMDAI KQAKNDGSAQ PLFIRPSAQW YSYEQRLEGD GSGVISGPPS FRFGGSRRRS
VTSSSTQAVR DGYGVWHVCY SMHSSRGELE RALKLLNPKE VISTTPRAGV CDFLTHLRDP
LPSSMPEGAF ILKAVDYPVS EDRELKRATT DHCSIPSKVI NNNAVESPKR STPLFGSAQF
PTLRFAAKTC PGIRGPKGSL
//
