ID A0A2K1JYI2_PHYPA Unreviewed; 645 AA.
AC A0A2K1JYI2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Arf-GAP domain-containing protein {ECO:0000259|PROSITE:PS50115};
GN ORFNames=PHYPA_013703 {ECO:0000313|EMBL:PNR46584.1};
OS Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR46584.1};
RN [1] {ECO:0000313|EMBL:PNR46584.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c10_10670V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=18079367; DOI=10.1126/science.1150646;
RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA Boore J.L.;
RT "The Physcomitrella genome reveals evolutionary insights into the conquest
RT of land by plants.";
RL Science 319:64-69(2008).
RN [2] {ECO:0000313|EMBL:PNR46584.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c10_10670V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=29237241; DOI=10.1111/tpj.13801;
RA Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA Schmutz J., Rensing S.A.;
RT "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT structure and evolution.";
RL Plant J. 93:515-533(2018).
RN [3] {ECO:0000313|EnsemblPlants:Pp3c10_10670V3.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (DEC-2020) to UniProtKB.
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DR EMBL; ABEU02000010; PNR46584.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1JYI2; -.
DR STRING; 3218.A0A2K1JYI2; -.
DR PaxDb; 3218-PP1S120_129V6-3; -.
DR EnsemblPlants; Pp3c10_10670V3.1; Pp3c10_10670V3.1; Pp3c10_10670.
DR EnsemblPlants; Pp3c10_10670V3.2; Pp3c10_10670V3.2; Pp3c10_10670.
DR EnsemblPlants; Pp3c10_10670V3.3; Pp3c10_10670V3.3; Pp3c10_10670.
DR EnsemblPlants; Pp3c10_10670V3.4; Pp3c10_10670V3.4; Pp3c10_10670.
DR EnsemblPlants; Pp3c10_10670V3.5; Pp3c10_10670V3.5; Pp3c10_10670.
DR EnsemblPlants; Pp3c10_10670V3.6; Pp3c10_10670V3.6; Pp3c10_10670.
DR Gramene; Pp3c10_10670V3.1; Pp3c10_10670V3.1; Pp3c10_10670.
DR Gramene; Pp3c10_10670V3.2; Pp3c10_10670V3.2; Pp3c10_10670.
DR Gramene; Pp3c10_10670V3.3; Pp3c10_10670V3.3; Pp3c10_10670.
DR Gramene; Pp3c10_10670V3.4; Pp3c10_10670V3.4; Pp3c10_10670.
DR Gramene; Pp3c10_10670V3.5; Pp3c10_10670V3.5; Pp3c10_10670.
DR Gramene; Pp3c10_10670V3.6; Pp3c10_10670V3.6; Pp3c10_10670.
DR InParanoid; A0A2K1JYI2; -.
DR OrthoDB; 5484367at2759; -.
DR Proteomes; UP000006727; Chromosome 10.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd08838; ArfGap_AGFG; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR044820; AGD14-like.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46085:SF3; ARF-GAP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46085; ARFGAP/RECO-RELATED; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000006727};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 11..129
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 167..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..393
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 645 AA; 71431 MW; 97E4C227E4119988 CRC64;
MGSRREDEKN EATIRRLLKI PENKRCINCN SLGPQYVCTT FATFVCTQCS GIHREFSHRI
KSISMAKFTA AEVAALQAGG NERAKKTFFR SMDPDRMYHS DSGSLDKLRD FINRVYEKRL
YTGDRPRTVQ QEVTAVELRR PDIKVERQPD FRSLSLDDHV ASKESVNRLK PDTIRNSVDN
RISPKYVGSP QAVPRPTRLS YDENEEKSPK SNGSRDRRNS SRPFSLRDFD ITPPPAQSIT
DILGDIPGLR IEVYKVPKGE HPPDHSKGAA VDARNAMQSQ SFRAVGNDTV TPAPDQKRVI
SASLIDMNGE TEATPVSRGI DDPFVETSQV SPSTSDSWAM FNTSSSSPAR PGYPASKSEI
SQSVDPGWGQ QSSSLDSWSS FGTPSPQAAS NQEHFTATPL SVSQNISGVV QPQRQRRELP
KDFFAPSFED VRQINLDMHR PHQMQPAFRP PQLDAPFESF YNMPPSTSFQ TQDLTQFQFS
PQMQPQPVES SQQMQSQLPT FTQRSRNPFD DDFEDNSSSV ISSATTGFSM QFPNMDSLRE
ALSPAMSMSS GVSTTGAVPQ NLPTNVASNE FGHSFTQLHN NFSPSGAFNF SPNQSISSFQ
ISPEQPNVSG GYASTHISGQ EGPYSSNQFY SQNIVRPAGG GNPFG
//
