ID A0A2K1K3F6_PHYPA Unreviewed; 1051 AA.
AC A0A2K1K3F6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Cation-transporting P-type ATPase N-terminal domain-containing protein {ECO:0000259|SMART:SM00831};
GN ORFNames=PHYPA_012784 {ECO:0000313|EMBL:PNR48308.1};
OS Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR48308.1};
RN [1] {ECO:0000313|EMBL:PNR48308.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c9_16670V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=18079367; DOI=10.1126/science.1150646;
RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA Boore J.L.;
RT "The Physcomitrella genome reveals evolutionary insights into the conquest
RT of land by plants.";
RL Science 319:64-69(2008).
RN [2] {ECO:0000313|EMBL:PNR48308.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c9_16670V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=29237241; DOI=10.1111/tpj.13801;
RA Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA Schmutz J., Rensing S.A.;
RT "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT structure and evolution.";
RL Plant J. 93:515-533(2018).
RN [3] {ECO:0000313|EnsemblPlants:Pp3c9_16670V3.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ABEU02000009; PNR48308.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1K3F6; -.
DR STRING; 3218.A0A2K1K3F6; -.
DR PaxDb; 3218-PP1S78_99V6-2; -.
DR EnsemblPlants; Pp3c9_16670V3.1; Pp3c9_16670V3.1; Pp3c9_16670.
DR EnsemblPlants; Pp3c9_16670V3.2; Pp3c9_16670V3.2; Pp3c9_16670.
DR EnsemblPlants; Pp3c9_16670V3.3; Pp3c9_16670V3.3; Pp3c9_16670.
DR EnsemblPlants; Pp3c9_16670V3.4; Pp3c9_16670V3.4; Pp3c9_16670.
DR Gramene; Pp3c9_16670V3.1; Pp3c9_16670V3.1; Pp3c9_16670.
DR Gramene; Pp3c9_16670V3.2; Pp3c9_16670V3.2; Pp3c9_16670.
DR Gramene; Pp3c9_16670V3.3; Pp3c9_16670V3.3; Pp3c9_16670.
DR Gramene; Pp3c9_16670V3.4; Pp3c9_16670V3.4; Pp3c9_16670.
DR InParanoid; A0A2K1K3F6; -.
DR OMA; WSENEPR; -.
DR OrthoDB; 203629at2759; -.
DR Proteomes; UP000006727; Chromosome 9.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005388; F:P-type calcium transporter activity; IBA:GO_Central.
DR GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GO_Central.
DR GO; GO:0006874; P:intracellular calcium ion homeostasis; IBA:GO_Central.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 3.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF4; CALCIUM-TRANSPORTING ATPASE 1, ENDOPLASMIC RETICULUM-TYPE-RELATED; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006727};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 64..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 857..879
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 979..999
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1011..1031
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..81
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
SQ SEQUENCE 1051 AA; 115336 MW; 32C34E40041FAC41 CRC64;
MAGEYFPAWA RSVQQCLDHF EVDVRSGLSQ SSIAKRRKQY GWNELEKEPG KPMWKLVLEQ
FDDMLVKILL VAALISFILA YIDGHSPDTS GIGAYVEPLV ILFILILNAI VGVWQESNAE
NALEALKEMQ SENAKVFRDG KYISDLPARE LVPGDIVELR VGDKVPADMR IVKLKTSTVR
VEQSSLTGES MSVTKTSYAV EENIELQGKE CMVFAGTTIV NGCFLSVVIT TGMKTEIGKI
QSQIQEASLE EADTPLKKKL DEFGELLTKV IGVICLLVWI INYKYFLSWE MKDGWPTNFQ
FSFEKCTYYF KIAVALAVAA IPEGLPAVIT TCLALGTRKM AAKNAIVRKL PSVETLGCTT
VICSDKTGTL TTNQMSVTDL VLNGPAAGVT RQFHVEGTTY SFLDGKIAGL RIGQLDPNIQ
SFAEIASLCN DAGILYQGNT FKATGMPTEA ALKVVVEKMG VPDPATQSII TNQRSSEALA
LNGEVPLGCN DWWSENEPRI AILEFDRSRK SMSCIVRKDG VNRLLVKGAV ENILERSTRV
QLSDGSVVKM TQSARDDLLA KLDSLSAKAL RCLGLAYKDD LQDLGDYDGD HHPGHARLLD
TSNYDKIESD LIFVGMAGIR DPPREEVRGA IEDCNEAGIR VMVITGDNKN TAEAICSEIG
IFKDGEDLKD KSFTGREFME FSPERRRKIL SGTGGRVFSR AEPKHKQDIV RILKEAGEVV
AMTGDGVNDA PALKLADIGV AMGIAGTEVA KEAADMVLAD DNFSTIVAAV GEGRSIYNNM
KAFIRYMISS NIGEVASIFM TAALGMPEGL VPVQLLWVNL VTDGPPATAL GFNPPDLDIM
QKPPRKSDDV LINAWVFFRY LVIGLYVGVA TVGAFALWYT QASFLGINLA ADGHTLVSFS
QLTHWGECST WKDFKVAPFT AGDLTLSFDD NPCDYFTTGK VKATTLSLSV LVAIEMFNSL
NALSEDGSLV SMPPWVNPWL LLAMGLSFSL HFLILYIPFL AKIFGIVPLS LLEWLLVLVV
SLPVILIDEV LKFIGRRMNQ RERQARKLKW A
//
