ID A0A2K1KKU2_PHYPA Unreviewed; 729 AA.
AC A0A2K1KKU2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=PHYPA_008073 {ECO:0000313|EMBL:PNR54396.1};
OS Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR54396.1};
RN [1] {ECO:0000313|EMBL:PNR54396.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c5_23480V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=18079367; DOI=10.1126/science.1150646;
RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA Boore J.L.;
RT "The Physcomitrella genome reveals evolutionary insights into the conquest
RT of land by plants.";
RL Science 319:64-69(2008).
RN [2] {ECO:0000313|EMBL:PNR54396.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c5_23480V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=29237241; DOI=10.1111/tpj.13801;
RA Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA Schmutz J., Rensing S.A.;
RT "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT structure and evolution.";
RL Plant J. 93:515-533(2018).
RN [3] {ECO:0000313|EnsemblPlants:Pp3c5_23480V3.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
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DR EMBL; ABEU02000005; PNR54396.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1KKU2; -.
DR STRING; 3218.A0A2K1KKU2; -.
DR PaxDb; 3218-PP1S23_154V6-1; -.
DR EnsemblPlants; Pp3c5_23480V3.1; Pp3c5_23480V3.1; Pp3c5_23480.
DR EnsemblPlants; Pp3c5_23480V3.2; Pp3c5_23480V3.2; Pp3c5_23480.
DR EnsemblPlants; Pp3c5_23480V3.3; Pp3c5_23480V3.3; Pp3c5_23480.
DR EnsemblPlants; Pp3c5_23480V3.4; Pp3c5_23480V3.4; Pp3c5_23480.
DR EnsemblPlants; Pp3c5_23480V3.5; Pp3c5_23480V3.5; Pp3c5_23480.
DR Gramene; Pp3c5_23480V3.1; Pp3c5_23480V3.1; Pp3c5_23480.
DR Gramene; Pp3c5_23480V3.2; Pp3c5_23480V3.2; Pp3c5_23480.
DR Gramene; Pp3c5_23480V3.3; Pp3c5_23480V3.3; Pp3c5_23480.
DR Gramene; Pp3c5_23480V3.4; Pp3c5_23480V3.4; Pp3c5_23480.
DR Gramene; Pp3c5_23480V3.5; Pp3c5_23480V3.5; Pp3c5_23480.
DR InParanoid; A0A2K1KKU2; -.
DR OrthoDB; 9585at2759; -.
DR Proteomes; UP000006727; Chromosome 5.
DR GO; GO:0009534; C:chloroplast thylakoid; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IBA:GO_Central.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR23076:SF37; ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1; 1.
DR PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000006727};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 277..413
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 729 AA; 78467 MW; F381EFD1C54F4438 CRC64;
MAWRLLMHEG SHVSKQLATS NALAGLGSHL KLSLYQLRLQ AISIENEGRR LLGCQRRQMS
SYTSNYARRL EHAEGGSKLG SEDKQVSLLK QLNKVDPESV IQWFESRPSS HHSSAAMAEY
VKALVKVDRL DESALLRTLQ QGAAIAGNGM RSETSMNVAS TAAPVLGSAG VMTKEGLLGT
PQAPIHMVTA EGGLKVQAWR TLRTLALGFL LISGVGALIE DRGIGKGLGL NEEVQPSMES
STKFSDVKGV DEAKAELEEI VHYLRDPQRF TSLGGKLPKG VLLVGPPGTG KTMLARAIAG
EAGVPFFYCS GSEFEEMFVG VGARRVRDLF SAAKKRAPCI IFMDEIDAIG GSRNPKDQQY
MKMTLNQLLV ELDGFKQNEG IIVVAATNFP ESLDKALVRP GRFDRHVVVP NPDVEGRRQI
LEVHMSKVPK SGDVDLSIIA RGTPGFSGAD LANLINVAAL KAAMDGKKDV SMTDLEFAKD
KIMMGSERKS AVISEESRRL TAYHEGGHAL VAIFTESALP VHKVTIVPRG MALGMVTQLP
DKDETSFSRK QMLARLDVCM GGRVAEELVF GEGEVTSGAS SDIVRATKLA REMVTKYGMS
KAVGVVAHNY EDDGKSMSTE TRLLVESEVR ELLQTAYENA KRILSTHQRE LHTLAATLLE
RETMTAVEIK TLLAQVKEQA NRANIPLFSP QQIVPTTTAQ VAQAAAANAA AAVAAAASAK
TKSAAPAGT
//
