ID A0A2K1PZ44_9GAMM Unreviewed; 718 AA.
AC A0A2K1PZ44;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Lysil_2244 {ECO:0000313|EMBL:PNS08068.1};
OS Lysobacter silvestris.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Lysobacter.
OX NCBI_TaxID=1645665 {ECO:0000313|EMBL:PNS08068.1, ECO:0000313|Proteomes:UP000236220};
RN [1] {ECO:0000313|EMBL:PNS08068.1, ECO:0000313|Proteomes:UP000236220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM20-91 {ECO:0000313|EMBL:PNS08068.1,
RC ECO:0000313|Proteomes:UP000236220};
RA Zhang D.-C., Albuquerque L., Franca L., Froufe H.J.C., Barroso C., Egas C.,
RA Da Costa M., Margesin R.;
RT "Lysobacter sylvestris genome.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNS08068.1}.
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DR EMBL; NPZB01000002; PNS08068.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1PZ44; -.
DR OrthoDB; 9808408at2; -.
DR Proteomes; UP000236220; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR42878:SF7; BACTERIOPHYTOCHROME; 1.
DR PANTHER; PTHR42878; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000236220};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 145..248
FT /note="CHASE"
FT /evidence="ECO:0000259|PROSITE:PS50839"
FT DOMAIN 500..710
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 718 AA; 80089 MW; C80489214FAE5E26 CRC64;
MPSQNEAADH FNQQAPVLFG VLAWICATVM VLLVWRNEQA IAQRESMVEL NSEAVLVESL
VKQRLDAMEL IMRGGASLIS GNTLPTADQW QGYVSGLDLG QRYSAVLGIG YGPYINRADL
PRFQQDWRDR TGELISIRPW GVRAEYAPVL FLATSGPGQE KLLGLDMYVE ATRHEAMQRA
MESGRPWLSG PVTLYRDTTA VPSMIFYTPV YRGGVRPMTV AARRAEMNGW VYIPFRVQQF
LDMTVKSVGR KMKLRISDET DTRRELVIAE DPGLTGRGAW KLISRSVPLY GRILRLDFFG
DADVGIERSA WVLWGGLPLA LAAGVITFLL ARTQARAQVL ARDMTRAQAR SEALFRSAMV
HSGIGMALLD DKARVVEVNP AFTQLFELGA DALRGTHFSD LLDQGSVGPA EQGEQNGMRQ
EIRRFARRNG ELRHVSLVYG KIPQGDGVDV KLLVQAEDIS ERVRNEARIR ALNRTLELRV
DARTRELSEA NHQLETFAYS VSHDLRAPLR AIDGFSRLLS ERHATVLDDV AQGYLARIRN
GARRMDDLIG AILKISRIGR GELQRHPIDL SALAQDVVEE LAATDPQRNF EVEIEPGLEV
VGDPSLVRTL MQNLIGNAWK FTQGRDPARI HFGRDQGSYF VEDNGVGFEP AYAGKLFQPF
QRLHGESEFA GHGIGLATVR RIVERHGGTI HAQGEVDRGA RFIFTLPDVP VDHDDYHV
//
